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Catalog Number Size Price
LS-C11635-0.1 0.1 mg $385 
Antibody

Monoclonal Mouse anti‑Human GZMB / Granzyme B Antibody (clone GB7, IHC) LS‑C11635

Monoclonal Mouse anti‑Human GZMB / Granzyme B Antibody (clone GB7, IHC) LS‑C11635

Note: This antibody replaces LS-C44293
Antibody:
GZMB / Granzyme B Mouse anti-Human Monoclonal (GB7) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$385
LS-C11635-0.1
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
GZMB / Granzyme B Mouse anti-Human Monoclonal (GB7) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Granzyme B antibody LS-C11635 is an unconjugated mouse monoclonal antibody to human Granzyme B (GZMB). Validated for IHC.
Target
Human GZMB / Granzyme B
Synonyms
GZMB | CCPI | CGL-1 | Cathepsin G-like 1 | CSP-B | CTLA-1 | CTLA1 | CGL1 | CSPB | Fragmentin 2 | GRB | HLP | Human lymphocyte protein | Fragmentin-2 | SECT | Lymphocyte protease | T-cell serine protease 1-3E | C11 | CTSGL1 | Cytotoxic serine protease B | Granzyme B | Granzyme-2
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Clone
GB7
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified
Immunogen
Recombinant Granzyme B.
Specificity
Recognizes the serine protease Granzyme B, which is expressed within the granules of cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death.
Applications
  • IHC
  • IHC - Paraffin (1:50 - 1:200)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
Presentation
TBS, 0.01% Thimerosal
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GZMB / Granzyme B
P10144 NM_004131 NP_004122.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/24/2024