Human GZMB / Granzyme B

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

GB10

Biotin. Also available Unconjugated.

Protein A purified

Unmodified

Purified human Granzyme B.

Recognizes the serine protease Granzyme B, which is expressed within the granules of cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death. Has been reported to function as a detection reagent in ELISA assays for soluble Granzyme B in conjunction with GB11 (MCA2120) as capture reagent.

• ELISA (1 µg/ml)
• Applications tested for the base form of this product only

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. ELISA: This antibody has been reported to function as a detection reagent in sandwich ELISA assays for soluble Granzyme B in conjunction with GB11 (LS-C44295) as capture reagent.

TBS, 0.001% Thimerosal, 1% BSA

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P10144 NCBI: NM_004131 NP_004122.2