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Anti-GZMB / Granzyme B Antibody (clone 4E4) LS-C174385


Wt. Vol. Conc. Price
- 100 µl 1 mg/ml $350
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular GZMB / Granzyme B Antibodies

Anti-GZMB / Granzyme B Antibody (clone GB11) LS-C44295
Mouse Monoclonal [clone GB11] (IgG1) to Human GZMB / Granzyme B
Human, Monkey, Rhesus monkey
IHC - Frozen, Immunoprecipitation, Flow Cytometry, ELISA
Anti-GZMB / Granzyme B Antibody (N-Terminus) IHC-plus™ LS-B2783
Rabbit Polyclonal to Human GZMB / Granzyme B
Human, Mouse, Rat
IHC - Paraffin
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 4E4] (IgG1) to Human GZMB / Granzyme B
IHC - Paraffin, Immunofluorescence, Western blot


Human GZMB / Granzyme B
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [4E4]
Protein A/G purified


  • IHC - Paraffin (1:150)
  • Immunofluorescence (1:100)
  • Western blot (1:2000)

Specificity and Use

GZMB / Granzyme B antibody was raised against human recombinant protein fragment corresponding to amino acids 21-247 of human GZMB(NP_004122) produced in E. coli.
Human Granzyme B


PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About GZMB / Granzyme B

P10144 NM_004131 NP_004122.2

GZMB Antibody, CCPI Antibody, CGL-1 Antibody, Cathepsin G-like 1 Antibody, CSP-B Antibody, CTLA-1 Antibody, CTLA1 Antibody, CGL1 Antibody, CSPB Antibody, Fragmentin 2 Antibody, GRB Antibody, HLP Antibody, Human lymphocyte protein Antibody, Fragmentin-2 Antibody, SECT Antibody, Lymphocyte protease Antibody, T-cell serine protease 1-3E Antibody, C11 Antibody, CTSGL1 Antibody, Cytotoxic serine protease B Antibody, Granzyme B Antibody, Granzyme-2 Antibody

This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.


IHC of paraffin-embedded Human lymphoma tissue using anti-GZMB mouse monoclonal antibody.


IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-GZMB mouse monoclonal antibody.


Anti-GZMB mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GZMB.

Western blot

Western blot
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GZMB (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GZMB.

Requested From: United States
Date Requested: 10/23/2016

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