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Anti-GZMB / Granzyme B Antibody (aa2-32) LS-C99306

Ordering

Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular GZMB / Granzyme B Antibodies

Anti-GZMB / Granzyme B Antibody (clone GB11) LS-C44295
Mouse Monoclonal [clone GB11] (IgG1) to Human GZMB / Granzyme B
Human, Monkey, Rhesus monkey
IHC - Frozen, Immunoprecipitation, Flow Cytometry, ELISA
Unconjugated
Anti-GZMB / Granzyme B Antibody (aa21-247, clone 4E6) LS-C338016
Mouse Monoclonal [clone 4E6] (IgG2a) to Human GZMB / Granzyme B
Human
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image

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Rabbit Polyclonal to Human GZMB / Granzyme B
Human, Mouse
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated

Details

Human GZMB / Granzyme B
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)

Specificity and Use

GZMB / Granzyme B antibody was raised against kLH-conjugated synthetic peptide between amino acids 2-32 from N-terminal region of human GZMB.
LS-E8301 - Lyophilized - 100 µg - $145.00
aa2-32

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About GZMB / Granzyme B

P10144 NM_004131 NP_004122.2

GZMB Antibody, CCPI Antibody, CGL-1 Antibody, Cathepsin G-like 1 Antibody, CSP-B Antibody, CTLA-1 Antibody, CTLA1 Antibody, CGL1 Antibody, CSPB Antibody, Fragmentin 2 Antibody, GRB Antibody, HLP Antibody, Human lymphocyte protein Antibody, Fragmentin-2 Antibody, SECT Antibody, Lymphocyte protease Antibody, T-cell serine protease 1-3E Antibody, C11 Antibody, CTSGL1 Antibody, Cytotoxic serine protease B Antibody, Granzyme B Antibody, Granzyme-2 Antibody

This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Immunohistochemistry

Immunohistochemistry
GZMB Antibody IHC of formalin-fixed and paraffin-embedded human Lymph tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

Western blot
Western blot of GZMB (arrow) using rabbit polyclonal GZMB Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GZMB gene.

Western blot

Western blot
Western blot of GZMB antibody in mouse stomach lysates (35 ug/lane). GZMB (arrow) was detected using the purified antibody.

Flow Cytometry

Flow Cytometry
GZMB Antibody flow cytometry of HL-60 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Requested From: United States
Date Requested: 12/3/2016

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