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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GUCY1B3 Antibody (aa189‑207) IHC‑plus™ LS‑B3342 Best Seller
Note: This antibody replaces LS-C50246
GUCY1B3 antibody LS-B3342 is an unconjugated rabbit polyclonal antibody to GUCY1B3 from human, mouse and rat. Validated for IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B3342-250
250 µl
Unavailable

Popular GUCY1B3 Products

Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6961 concentration 5 ug/ml.
Species: Rat, Human, Bat
Applications: IHC, IHC - Paraffin, Western blot
Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7603 dilution 1:200.
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Western blot of GCS-beta-1 antibody
Species: Human, Mouse, Rat
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: Immunofluorescence, Western blot, ELISA

Product Description

GUCY1B3 antibody LS-B3342 is an unconjugated rabbit polyclonal antibody to GUCY1B3 from human, mouse and rat. Validated for IHC. Tested on 20 paraffin-embedded human tissues.
About GUCY1B3
GUCY1B3 encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. Q02153 NM_000857 NP_000848.1

GUCY1B3 Antibody, GC-S-beta-1 Antibody, GC-SB3 Antibody, GCS-beta-1 Antibody, GUC1B3 Antibody, GUCB3 Antibody, GUCSB3 Antibody, GUCY1B1 Antibody, GCS-beta-3 Antibody


Specifications

Target
Human GUCY1B3
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GUCY1B3 antibody was raised against a synthetic peptide from aa 189-207 of human guanylyl cyclase beta 1, soluble.
Epitope
aa189-207
Usage
Immunohistochemistry: LS-B3342 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3342 was determined to be 10 ug/ml.
Presentation
10 mM PBS, pH 7.4, 1% BSA, 0.09% sodium azide
Storage
Store at 2-8°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Immunohistochemistry

Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.
Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.

Immunohistochemistry

Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.
Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.

Immunohistochemistry

Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.
Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.

Immunohistochemistry

Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.
Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.

Immunohistochemistry

Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.
Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.

Immunohistochemistry

Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.
Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.

Immunohistochemistry

Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.
Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.

Immunohistochemistry

Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.
Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3342 concentration 10 ug/ml.


Requested From: 
Date Requested: 6/21/2018

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