Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG2b) to Human GSK3B / GSK3 Beta
Western blot, Immunoprecipitation, ELISA
Sepharose 4B Conjugated
Human GSK3B / GSK3 Beta
Human (tested or 100% immunogen sequence identity)
Specificity and Use
Recognizes human GSK3b.
Western Blot. Enzyme-Linked-Immunosorbent-Assay (ELISA). Immunoprecipitation. Immunoprecipitation: 40ul. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
GSK3B Antibody, GSK-3 beta Antibody, GSK3 beta Antibody, GSK3beta Antibody, GSK3beta isoform Antibody, TPKI Antibody, GSK 3beta Antibody, Tau protein kinase I Antibody, ZGSK-3beta Antibody
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Requires primed phosphorylation of the majority of its substrates.