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Anti-GSK3A / GSK3 Alpha Antibody (phospho-Ser9) LS-C66833

Ordering

Wt. Vol. Conc. Price
- 100 µl - $485
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular GSK3A / GSK3 Alpha Antibodies

Anti-GSK3A / GSK3 Alpha Antibody (aa203-219) LS-C23951
Mouse Monoclonal (IgG1) to Drosophila GSK3A / GSK3 Alpha
Drosophila, Insect
ICC, Western blot
Unconjugated
Anti-GSK3A / GSK3 Alpha Antibody (clone 13A190, FITC) LS-C183384
Mouse Monoclonal [clone 13A190] (IgG1) to Human GSK3A / GSK3 Alpha
Human
Flow Cytometry
FITC Conjugated
Anti-GSK3A / GSK3 Alpha Antibody (aa347-376, PE) LS-C214982
Rabbit Polyclonal (IgG) to Mouse GSK3A / GSK3 Alpha
Mouse
IHC, Western blot, ELISA
PE Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Rat GSK3A / GSK3 Alpha
Rat
Western blot
Unconjugated

Details

Rat GSK3A / GSK3 Alpha
Rabbit
Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot

Specificity and Use

GSK3A / GSK3 Alpha antibody was raised against phosphopeptide corresponding to amino acid residues surrounding the phospho- Ser9 of GSK3beta. Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
pSer9
The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with human, mouse, chicken, bovine, canine, non-human primate, Zebrafish and Xenopus based on the fact that these species have 100% homology with the amino acid sequence used as antigen. Specific for the ~46k GSK3b protein phosphorylated at Ser9. Also weakly labels the ~51k GSK3a band due to the high degree of homology between the 2 subunits. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide.
Suitable for use in Western Blot. Positive control: Rat cortex lysate.

Packaging

10 mM HEPES, pH 7.5, 150 mM sodium chloride, 100 ug/ml BSA, 50% glycerol.
For research use only.

About GSK3A / GSK3 Alpha

P49840 NM_019884 NP_063937.2

GSK3A Antibody, GSK-3 alpha Antibody, GSK3 alpha Antibody

Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis.

Requested From: United States
Date Requested: 12/2/2016

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