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Anti-GRN / Granulin Antibody (C-Terminus) IHC-plus™ LS-B3158

Note: This antibody replaces LS-C17498


Wt. Vol. Conc. Price
50 µg - 0.25 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular GRN / Granulin Antibodies

Anti-GRN / Granulin Antibody LS-C75078
Mouse Monoclonal (IgG2a) to Human GRN / Granulin
Western blot, Immunoprecipitation, ELISA
Anti-GRN / Granulin Antibody (C-Terminus) IHC-plus™ LS-B3158
Rabbit Polyclonal (IgG) to Human GRN / Granulin
IHC - Paraffin, Western blot, Immunoprecipitation
Immunohistochemistry Image
Anti-GRN / Granulin Antibody (aa18-589, clone 333731) LS-C150233
Rat Monoclonal [clone 333731] (IgG2a) to Mouse GRN / Granulin
IHC, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human GRN / Granulin
IHC - Paraffin, Western blot, Immunoprecipitation


Human GRN / Granulin
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • IHC - Paraffin (5 µg/ml)
  • Western blot (1 - 3 µg/ml)
  • Immunoprecipitation

Specificity and Use

GRN / Granulin antibody was raised against synthetic peptide derived from the C-terminal region of human PCDGF (PC cell-derived growth factor, GP88, acrogranin, granulin precursor, epithelin precursor, or progranulin).
Recognizes human PCDGF protein at ~64-88kD.
Immunohistochemistry: LS-B3158 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3158 was determined to be 5 ug/ml. Positive control: Human MDA-MB-231 breast adenocarcinoma, PC-3 prostate adenocarcinoma (bone metastatic site), HeLa cervical carcinoma, and HT1080 fibrosarcoma lysates.


PBS, pH 7.4, 0.1% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About GRN / Granulin

P28799 NM_002087 NP_002078.1

GRN Antibody, Acrogranin Antibody, CLN11 Antibody, Epithelin precursor Antibody, GEP Antibody, gp88 Antibody, Granulin Antibody, Granulin-epithelin Antibody, Granulins Antibody, PC cell-derived growth factor Antibody, PCDGF Antibody, PEPI Antibody, PGRN Antibody, Proepithelin Antibody, Progranulin Antibody

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc.


Anti-GRN / Granulin antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3158 concentration 5 ug/ml.

Requested From: United States
Date Requested: 10/27/2016

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