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Anti-GRN / Granulin Antibody (aa248-259) LS-C154960

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular GRN / Granulin Antibodies

Anti-GRN / Granulin Antibody LS-C75078
Mouse Monoclonal (IgG2a) to Human GRN / Granulin
Human
Western blot, Immunoprecipitation, ELISA
Unconjugated
Anti-GRN / Granulin Antibody (C-Terminus) IHC-plus™ LS-B3158
Rabbit Polyclonal (IgG) to Human GRN / Granulin
Human
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-GRN / Granulin Antibody (aa18-589, clone 333731) LS-C150233
Rat Monoclonal [clone 333731] (IgG2a) to Mouse GRN / Granulin
Mouse
IHC, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human GRN / Granulin
Human, Monkey, Mouse, Rat, Hamster
Western blot, ELISA
Unconjugated

Details

Human GRN / Granulin
Goat
Human, Monkey, Mouse, Rat, Hamster (tested or 100% immunogen sequence identity)
Bat, Rabbit (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (1 - 3 µg/ml)
  • ELISA (1:8000)

Specificity and Use

GRN / Granulin antibody was raised against synthetic peptide PQDTVCDLIQSK from an internal of human GRN / Granulin (NP_002078.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Hamster (100%); Chimpanzee, Galago, Elephant, Panda, Bat, Rabbit (92%); Dog, Bovine, Horse, Guinea pig (83%).
LS-E27830 - Lyophilized - 100 µg - $145.00
aa248-259
Human GRN / Granulin. This antibody is expected to recognize the C-Terminal part of Granulin-3.
Peptide ELISA: antibody detection limit dilution 1:8000. Western blot: Approx 75kD band observed in lysates of cell lines A431, A549 and HeLa (calculated MW of 63.5kD according to NP_002078.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (He and Bateman, Cancer Res. 1999 Jul 1;59(13):3222-9. PMID: 10397269). Recommended concentration: 1-3 ug/ml.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About GRN / Granulin

P28799 NM_002087 NP_002078.1

GRN Antibody, Acrogranin Antibody, CLN11 Antibody, Epithelin precursor Antibody, GEP Antibody, gp88 Antibody, Granulin Antibody, Granulin-epithelin Antibody, Granulins Antibody, PC cell-derived growth factor Antibody, PCDGF Antibody, PEPI Antibody, PGRN Antibody, Proepithelin Antibody, Progranulin Antibody

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc.

Western blot

Western blot
GRN antibody (1 ug/ml) staining of A431 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
 

Requested From: United States
Date Requested: 12/7/2016

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