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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GRM3 / MGLUR3 Antibody (N‑Terminus) IHC‑plus™ LS‑A899
MGLUR3 antibody LS-A899 is an unconjugated rabbit polyclonal antibody to MGLUR3 (GRM3) from human, mouse, rat and other species. Validated for ICC and IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-A899-50
50 µg (1 mg/ml)
$425
In Stock for Immediate Shipment

Popular GRM3 / MGLUR3 Products

Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, ICC, Western blot
Anti-GRM3 / MGLUR3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Bovine, Horse, Pig
Applications: IHC, IHC - Paraffin, ICC, Western blot
Western blot of GRM3 / MGLUR3 antibody.
Species: Human, Rat, Pig
Applications: Western blot
Immunohistochemistry of paraffin-embedded human liver cancer using GRM3 antibody at dilution of 1:200 (x400 lens).
Species: Human, Mouse
Applications: IHC, Immunofluorescence, Western blot

Product Description

MGLUR3 antibody LS-A899 is an unconjugated rabbit polyclonal antibody to MGLUR3 (GRM3) from human, mouse, rat and other species. Validated for ICC and IHC. Tested on 20 paraffin-embedded human tissues.

Specifications

Target
Human GRM3 / MGLUR3
Synonyms
GRM3, GPRC1C, GLUR3, MGLUR3, MGlu3
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Hamster, Horse, Pig (tested or 100% immunogen sequence identity)
Predicted
Rabbit, Chicken (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (16 µg/ml)
  • ICC
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GRM3 / MGLUR3 antibody was raised against synthetic 16 amino acid peptide from N-terminal extracellular domain of human GRM3 / MGLUR3. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Horse, Pig, Opossum, Platypus, Lizard (100%); Rabbit, Turkey, Zebra finch, Chicken (94%).
Blocking Peptide
LS-E29533 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A899. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human GRM3 / MGLUR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About GRM3 / MGLUR3
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. Q14832 NM_000840 NP_000831.2


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Images

Immunocytochemistry

Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.

Immunocytochemistry

Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with GRM3 / MGLUR3.
Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with GRM3 / MGLUR3.

Immunohistochemistry

Anti-GRM3 / MGLUR3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM3 / MGLUR3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-GRM3 / MGLUR3 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM3 / MGLUR3 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-GRM3 / MGLUR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM3 / MGLUR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunocytochemistry

Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.

Immunocytochemistry

Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with GRM3 / MGLUR3.
Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with GRM3 / MGLUR3.

Immunohistochemistry

Anti-GRM3 / MGLUR3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM3 / MGLUR3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-GRM3 / MGLUR3 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM3 / MGLUR3 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-GRM3 / MGLUR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM3 / MGLUR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunocytochemistry

Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.

Immunocytochemistry

Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with GRM3 / MGLUR3.
Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with GRM3 / MGLUR3.

Immunohistochemistry

Anti-GRM3 / MGLUR3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM3 / MGLUR3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-GRM3 / MGLUR3 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM3 / MGLUR3 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-GRM3 / MGLUR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM3 / MGLUR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunocytochemistry

Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.

Immunocytochemistry

Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with GRM3 / MGLUR3.
Anti-GRM3 / MGLUR3 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with GRM3 / MGLUR3.

Immunohistochemistry

Anti-GRM3 / MGLUR3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM3 / MGLUR3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-GRM3 / MGLUR3 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM3 / MGLUR3 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-GRM3 / MGLUR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM3 / MGLUR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: United States
Date Requested: 11/15/2018

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