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Anti-GRK5 Antibody (N-Terminus) IHC-plus™ LS-A3470

Note: This antibody replaces LS-C67126, LS-C67125, LS-C42538

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
Inquire for larger quantities
Same day shipping In Stock - Same day shipping

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular GRK5 Antibodies

Anti-GRK5 Antibody (Internal) IHC-plus™ LS-A3034
Rabbit Polyclonal to Human GRK5
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-GRK5 Antibody (N-Terminus) IHC-plus™ LS-A3470
Rabbit Polyclonal to Human GRK5
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-GRK5 Antibody (Internal) IHC-plus™ LS-A3030
Rabbit Polyclonal to Human GRK5
Human, Monkey, Mouse, Rat, Bat, Bovine, Horse, Pig, Chicken
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed In Stock In Stock
Rabbit Polyclonal to Human GRK5
Human
IHC - Paraffin
Unconjugated

Details

Human GRK5
Rabbit
Human (tested or 100% immunogen sequence identity)
Monkey, Bovine, Horse (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

IHC - Paraffin (6 µg/ml)

Specificity and Use

GRK5 antibody was raised against synthetic 15 amino acid peptide from N-terminus of human GRK5. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Orangutan, Gibbon, Marmoset, Bovine, Horse (93%); Dog, Elephant, Panda, Pig (87%); Mouse, Rat, Bat (80%).
LS-E28760 - Liquid - 50 µg - $145.00
N-Terminus
Human GRK5. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GRK1 (47%).
Immunohistochemistry: LS-A3470 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A3470 was determined to be 6 ug/ml.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About GRK5

P34947 NM_005308 NP_005299.1

GRK5 Antibody, FP2025 Antibody, GPRK5 Antibody

Serine/threonine kinase that phosphorylates preferentially the activated forms of a variety of G-protein-coupled receptors (GPCRs). Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation. Phosphorylates a variety of GPCRs, including adrenergic receptors, muscarinic acetylcholine receptors (more specifically Gi-coupled M2/M4 subtypes), dopamine receptors and opioid receptors.

Immunohistochemistry

Immunohistochemistry
Anti-GRK5 antibody LS-A3470 IHC of human myocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
 

Requested From: United States
Date Requested: 12/10/2016

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