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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GRIA4 / GLUR4 Antibody (aa889‑902) LS‑C15373 Best Seller
Antibody
GLUR4 antibody LS-C15373 is an unconjugated rabbit polyclonal antibody to GLUR4 (GRIA4) from mouse and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C15373-50
50 µg (1 mg/ml)
Unavailable
LS-C15373-100
100 µg
Unavailable

Popular GRIA4 / GLUR4 Products

Anti-GRIA4 / GLUR4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3606 concentration 5 ug/ml.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Rabbit, Chicken
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
GRIA4 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
GRIA4 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA

Product Description

GLUR4 antibody LS-C15373 is an unconjugated rabbit polyclonal antibody to GLUR4 (GRIA4) from mouse and rat. Validated for IHC and WB.
About GRIA4 / GLUR4
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. P48058 NM_000829 NP_000820.3

GRIA4 Antibody, GluA4 Antibody, GluR-4 Antibody, GLUR4 Antibody, GLUR4C Antibody, Glutamate receptor type d Antibody, GluR-D Antibody, GLURD Antibody, Glutamate receptor 4 Antibody


Specifications

Target
Rat GRIA4 / GLUR4
Host
Rabbit
Reactivity
Rat, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen (1:10 - 1:50)
  • Western blot (1 - 3 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GRIA4 / GLUR4 antibody was raised against carboxy terminus peptide of rat GluR4 conjugated to BSA with glutaraldehyde (RQSSGLAVIASDLP). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus, Trachemys (100%).
Epitope
aa889-902
Specificity
Western blot of rat brain shows a single band co-migrating with GluR4 expressed in transfected cells. No cross-reaction with GluR1-3. The antibody appears to recognize GluR4 in several other species, but has not been extensively characterized in these cases. Species Reactivity: rat and mouse.
Usage
Can be used for immunocytochemistry using paraformaldehyde or paraformaldehyde/glutaraldehyde fixed tissue with light and electron microscopy. Cryostat and vibratome sections can be used with or without Triton X-100 treatment. Final concentrations used were 1-3 ug/ml. Western blot analysis can be done at final concentrations of 0.5-2.5 ug/ml.
Presentation
PBS, 0.05% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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