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Anti-GRIA2 / GLUR2 Antibody LS-C43151

Ordering

Wt. Vol. Conc. Price
- 100 µl - $505
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular GRIA2 / GLUR2 Antibodies

Anti-GRIA2 / GLUR2 Antibody (Ser880) IHC-plus™ LS-B1473
Rabbit Polyclonal (IgG) to Human GRIA2 / GLUR2
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-GRIA2 / GLUR2 Antibody (aa175-430) IHC-plus™ LS-B2811
Mouse Monoclonal (IgG2a) to Human GRIA2 / GLUR2
Human, Monkey, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Rat GRIA2 / GLUR2
Rat, Human
Western blot
Unconjugated

Details

Rat GRIA2 / GLUR2
Rabbit
Rat, Human (tested or 100% immunogen sequence identity)
Monkey, Mouse, Chicken, Zebrafish (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Purified
Unmodified

Applications

Western blot (1:1000)

Specificity and Use

GRIA2 / GLUR2 antibody was raised against keyhole limpet hemocyanin conjugated synthetic peptide corresponding to an amino acid sequence within rat GluR2.
Recognizes glutamate receptor subunit 2 (GluR2), a component of the AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid) group of ionotropic glutamate receptors, which play a key role at excitatory synapses, including synaptic transmission, stabilization and plasticity. GluR2 is possibly the most important of the AMPA receptor subunits, responsible for AMPA receptor rectifying properties, control of ion flow and in particular the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2(R) form, containing a critical arginine residue (as opposed to a glutamine residue) in the Transmembrane region 2 (TM2) domain, thereby rendering native AMPA receptors impermeable to calcium.
Western Blot: LS-C43151 detects a band of approximately 100 kD in rat brain hippocampus cell lysates.

Packaging

10 mM HEPES, pH 7.5, 0.09% sodium azide, 0.01% BSA, 50% glycerol.
For research use only.

About GRIA2 / GLUR2

P42262 NM_000826 NP_000817.2

GRIA2 Antibody, AMPA 2 Antibody, GluR-K2 Antibody, Glutamate receptor 2 Antibody, HBGR2 Antibody, GluA2 Antibody, GluR-2 Antibody, GluR-B Antibody, GLUR2 Antibody, GLURB Antibody

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4.

Requested From: United States
Date Requested: 12/10/2016

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