Rat GRIA1 / GLUR1

Rabbit

Rat (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

Synthetic peptide corresponding to the C-Terminus of the native molecule conjugated to Bovine Serum Albumin.

C-Terminus

Recognizes the glutamate receptor 1 (also known as AMPA) which acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Linked to immobilized Protein A immunoprecipitates detergent-solubilized receptor from brain or transfected cells.

• IHC - Frozen (1 - 3 µg/ml)
• Western blot (0.5 - 2.5 µg/ml)
• Immunoprecipitation

Immunohistology: Paraformaldehyde or paraformaldehyde/glutaraldehyde are suitable. Cryostat and vibratome sections can be used with or without Triton X-100 treatment.

PBS, 0.09% Sodium Azide

Reconstitute with distilled water.

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P42261 NCBI: NM_000827 NP_000818.2