Rat, Human, Monkey, Hamster
(tested or 100% immunogen sequence identity)
- IHC - Frozen (1 - 3 µg/ml)
- Western blot (0.5 - 2.5 µg/ml)
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GRIA1 / GLUR1 antibody was raised against synthetic peptide corresponding to the C terminal region of the native molecule conjugated to Bovine Serum Albumin. ( C-TERMINAL ).
Recognizes the glutamate receptor 1 (also known as AMPA) which acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Linked to immobilized Protein A immunoprecipitates detergent-solubilized receptor from brain or transfected cells.
Immunohistology: Paraformaldehyde or paraformaldehyde/glutaraldehyde are suitable. Cryostat and vibratome sections can be used with or without Triton X-100 treatment.
Lyophilized, PBS, 0.09% sodium azide, 1% BSA.
50 µl Distilled Water.
For research use only.
This antibody carries the LSBio 100% Guarantee.