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Gravin / AKAP12

A kinase (PRKA) anchor protein 12

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Gene Name: A kinase (PRKA) anchor protein 12
Synonyms: AKAP12, A-kinase anchor protein 12, AKAP-12, AKAP250, AKAP 250, Gravin, Kinase scaffold protein gravin, Myasthenia gravis autoantigen, SSeCKS
Target Sequences: NM_005100 NP_005091.2 Q02952

☰ Filters
Antibodies (23)
Proteins (6)
ELISA Kits (2)
Over-Expression Lysate (4)
Primary (23)
Recombinant (2)
Sandwich (2)
Gravin / AKAP12 (31)
Human (23)
Mouse (1)
Rat (2)
Bovine (1)
IHC (10)
IHC-P (2)
WB (18)
ELISA (6)
ICC (1)
IF (3)
IP (3)
Peptide-ELISA (3)
rabbit (18)
mouse (3)
goat (1)
sheep (1)
Product Group
IHCPlus (1)
IgG (10)
IgG2b (2)
IgG2b,k (1)
monoclonal mc (3)
polyclonal pc (20)
3C3 (1)
OTI1B6 (2)
96-Well Strip Plate (2)
APC (1)
APC Conjugated (1)
Biotin Conjugated (1)
Carrier-free (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (16)
aa1485-1782 (8)
aa266-557 (2)
270-350 aa, Internal (1)
aa1645-1658 (1)
aa1650-1700 (1)
aa1719-1782 (1)
aa1731-1781 (1)
aa301-350 (1)
No (31)
Plasma (2)
Serum (2)
Tissue Homogenates (1)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (4)
Human (4)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Gravin / AKAP12 Antibody - Anti-Gravin / AKAP12 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.
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Gravin / AKAP12 Rabbit anti-Human Polyclonal (aa1719-1782) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$485
Gravin / AKAP12 Antibody - Western blotting total cellular protein from cultured rat aortic smooth muscle cells was prepared and analyze. The protein was transferred to a PVDF membrane, blocked 1XTBS, 0.1% tween 20/ 5%NFDM, probed with 5 g/ml of pre-immune serum 5 ug of SSeCKS – myristylated (PKC) substrate antibody (a 3 second exposure is shown). The blot was then washed and probed with monoclonal anti-sheep IgG coupled to HRP 1:10,000, and detected with luminol.
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Gravin / AKAP12 Sheep anti-Rat Polyclonal Antibody
Bovine, Rat
IHC, IP, WB
Unconjugated
250 µg/$466
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Gravin / AKAP12 Goat anti-Mouse Polyclonal (aa1645-1658) Antibody
Mouse, Rat
Peptide-ELISA
Unconjugated
100 µg/$401
Gravin / AKAP12 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using AKAP12 Antibody. The picture on the right is blocked with the synthesized peptide.
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Gravin / AKAP12 Rabbit anti-Human Polyclonal (aa301-350) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
Select
Gravin / AKAP12 Rabbit anti-Human Polyclonal (270-350 aa, Internal) Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Gravin / AKAP12 Antibody - Immunohistochemical staining of paraffin-embedded Human adult heart tissue within the normal limits using anti-AKAP12 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120 oC for 3 min. (1:500)
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Gravin / AKAP12 Mouse anti-Human Monoclonal (aa266-557) (OTI1B6) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
Gravin / AKAP12 Antibody - Immunohistochemical staining of paraffin-embedded Human adult heart tissue within the normal limits using anti-AKAP12 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120 oC for 3 min. (1:500)
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Gravin / AKAP12 Mouse anti-Human Monoclonal (aa266-557) (Carrier-free) (OTI1B6) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Gravin / AKAP12 Antibody - Immunohistochemistry of paraffin-embedded Human brain using AKAP12 Polyclonal Antibody at dilution of 1:40.
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Gravin / AKAP12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Gravin / AKAP12 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue, using AKAP12 antibody.
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Gravin / AKAP12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
Select
Gravin / AKAP12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
Gravin / AKAP12 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using AKAP12 Polyclonal Antibody at dilution of 1:40.
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Gravin / AKAP12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Gravin / AKAP12 Antibody - Detection limit for recombinant GST tagged AKAP12 is approximately 3 ng/ml as a capture antibody.
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Gravin / AKAP12 Mouse anti-Human Monoclonal (3C3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
Gravin / AKAP12 Rabbit anti-Human Polyclonal (aa1650-1700) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
Gravin / AKAP12 Rabbit anti-Human Polyclonal (aa1731-1781) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Gravin / AKAP12 Antibody - Western blot analysis of AKAP12 using Jurkat whole cells lysates
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Gravin / AKAP12 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Gravin / AKAP12 Antibody - Western blot of Gravin / AKAP12 antibody.
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Gravin / AKAP12 Rabbit anti-Human Polyclonal (aa1485-1782) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
Gravin / AKAP12 Antibody - Western blot of Gravin / AKAP12 antibody.
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Gravin / AKAP12 Rabbit anti-Human Polyclonal (aa1485-1782) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
Gravin / AKAP12 Antibody - Western blot of Gravin / AKAP12 antibody.
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Gravin / AKAP12 Rabbit anti-Human Polyclonal (aa1485-1782) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
Gravin / AKAP12 Antibody - Western blot of Gravin / AKAP12 antibody.
Select
Gravin / AKAP12 Rabbit anti-Human Polyclonal (aa1485-1782) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
Gravin / AKAP12 Antibody - Western blot of Gravin / AKAP12 antibody.
Select
Gravin / AKAP12 Rabbit anti-Human Polyclonal (aa1485-1782) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Gravin / AKAP12 Antibody - Western blot of Gravin / AKAP12 antibody.
Select
Gravin / AKAP12 Rabbit anti-Human Polyclonal (aa1485-1782) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Gravin / AKAP12 Antibody - Western blot of Gravin / AKAP12 antibody.
Select
Gravin / AKAP12 Rabbit anti-Human Polyclonal (aa1485-1782) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
Gravin / AKAP12 Antibody - Western blot of Gravin / AKAP12 antibody.
Select
Gravin / AKAP12 Rabbit anti-Human Polyclonal (aa1485-1782) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Gravin / AKAP12 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
191.3 kDa
100 µg/$710
Gravin / AKAP12 Protein - Recombinant  A Kinase Anchor Protein 12 By SDS-PAGE
Select
E. coli
His-T7
35.8 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
Viewing 1-25 of 31 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).