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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GPR37L1 Antibody (N‑Terminus) IHC‑plus™ LS‑A404
GPR37L1 antibody LS-A404 is an unconjugated rabbit polyclonal antibody to human GPR37L1. Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-A404-50
50 µg (1 mg/ml)
Unavailable
In Stock for Immediate Shipment

Popular GPR37L1 Products

Anti-GPR37L1 antibody LS-A405 IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human
Applications: IHC, IHC - Paraffin
Anti-GPR37L1 antibody LS-A406 IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human
Applications: IHC, IHC - Paraffin
Antibody
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GPR37L1 antibody LS-C146300 Western blot of Fetal Brain lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Product Description

GPR37L1 antibody LS-A404 is an unconjugated rabbit polyclonal antibody to human GPR37L1. Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues.
About GPR37L1
Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade. O60883 NM_004767 NP_004758.3

GPR37L1 Antibody, ETBRLP2 Antibody, ET(B)R-LP-2 Antibody, ETBR-LP-2 Antibody, GPCR/CNS2 Antibody


Specifications

Target
Human GPR37L1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • ELISA
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GPR37L1 antibody was raised against synthetic 18 amino acid peptide from N-terminal extracellular domain of human GPR37L1. Percent identity with other species by BLAST analysis: Gorilla, Gibbon (100%); Human, Monkey, Marmoset (94%); Hamster (89%); Mouse, Rat (83%).
Blocking Peptide
LS-E28867 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A404. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human GPR37L1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FOXR1 (50%).
Usage
Immunohistochemistry: LS-A404 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A404 was determined to be 10 ug/ml.
Presentation
PBS, less than 0.1% sodium azide.
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Immunohistochemistry

Anti-GPR37L1 antibody LS-A404 IHC of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR37L1 antibody LS-A404 IHC of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-GPR37L1 antibody LS-A404 IHC of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR37L1 antibody LS-A404 IHC of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-GPR37L1 antibody LS-A404 IHC of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR37L1 antibody LS-A404 IHC of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-GPR37L1 antibody LS-A404 IHC of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR37L1 antibody LS-A404 IHC of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: 
Date Requested: 7/19/2018

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