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Anti-GPR3 Antibody (Extracellular Domain) IHC-plus™ LS-A121

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
Inquire for larger quantities
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Most Popular GPR3 Antibodies

Anti-GPR3 Antibody (Extracellular Domain) IHC-plus™ LS-A121
Rabbit Polyclonal to Human GPR3
Human, Monkey, Mouse, Rat, Hamster
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-GPR3 Antibody (aa229-238) LS-C61748
Goat Polyclonal to Human GPR3
Human, Monkey, Mouse, Rat, Bovine, Hamster, Pig, Rabbit
Western blot, ELISA
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed In Stock In Stock Publications Publications (2)
Rabbit Polyclonal to Human GPR3
Human, Monkey, Mouse, Rat, Hamster
IHC - Paraffin
Unconjugated

Details

Human GPR3
Rabbit
Human, Monkey, Mouse, Rat, Hamster (tested or 100% immunogen sequence identity)
Rabbit (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

IHC - Paraffin (6 µg/ml)

Specificity and Use

GPR3 antibody was raised against synthetic 15 amino acid peptide from 2nd extracellular domain of human GPR3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster (100%); Rabbit (93%); Bovine, Panda, Pig (80%).
LS-E28181 - Liquid - 50 µg - $145.00
Extracellular Domain
Human GPR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

Publications (2)

1
Premature ovarian aging in mice deficient for Gpr3. Ledent C, Demeestere I, Blum D, Petermans J, Hmlinen T, Smits G, Vassart G. Proceedings of the National Academy of Sciences of the United States of America. 2005 102:8922-6. (ICC; Mouse) [PubMed:15956199] [PMC:PMC1150279]
2
The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons. Thathiah A, Spittaels K, Hoffmann M, Staes M, Cohen A, Horr K, Vanbrabant M, Coun F, Baekelandt V, Delacourte A, Fischer DF, Pollet D, De Strooper B, Merchiers P. Science (New York, N.Y.). 2009 323:946-51. (IHC; Human) [PubMed:19213921]

About GPR3

P46089 NM_005281 NP_005272.1

GPR3 Antibody, ACCA Antibody, ACCA orphan receptor Antibody, G protein-coupled receptor 3 Antibody, GPCR3 Antibody, Hacca Antibody, G-protein coupled receptor 3 Antibody

GPR3 has been identified as a constitutively active lysophospholipid/lysosphingolipid receptor. GPR3 receptor is a link in communication between the somatic cells and oocyte of the ovarian follicle where GPR3 maintains meiotic arrest in mouse oocytes. Oocytes from Gpr3 knockout mice resume meiosis within antral follicles, independently of an increase in luteinizing hormone, and this phenotype Mice deficient in GPR3 exhibit premature ovarian failure due to early oocyte aging (Ledent et al.

Immunohistochemistry

Immunohistochemistry
Anti-GPR3 antibody LS-A121 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-GPR3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: United States
Date Requested: 12/5/2016

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