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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GPR143 Antibody (Cytoplasmic Domain) LS‑C94187
Antibody
GPR143 antibody LS-C94187 is an unconjugated rabbit polyclonal antibody to human GPR143. Validated for IHC and WB.
Catalog
Size
Price
LS-C94187-500
500 µg (1 mg/ml)
Unavailable

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Product Description

GPR143 antibody LS-C94187 is an unconjugated rabbit polyclonal antibody to human GPR143. Validated for IHC and WB.
About GPR143
Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca2+ influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand-dependent signaling occurs through a G(q)-mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. P51810 NM_000273 NP_000264.2

GPR143 Antibody, G-protein coupled receptor 143 Antibody, G protein-coupled receptor 143 Antibody, NYS6 Antibody, OA1 Antibody, Ocular albinism 1 Antibody, Ocular albinism type 1 protein Antibody


Specifications

Target
Human GPR143
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GPR143 antibody was raised against synthetic peptide from the 4th cytoplasmic domain of human ocular albinism type 1 protein (G protein-coupled receptor 143 or GPR143, OA1) conjugated to an immunogenic carrier protein.
Epitope
Cytoplasmic Domain
Specificity
Specific for OA1.
Usage
IHC: Antigen retrieval is essential for use on paraffin sections.
Presentation
Lyophilized. Centrifuge to remove any insoluble material
Reconstitution
500 µl Sterile water
Storage
Maintain lyophilized and reconstituted antibodies at -20°C for long term storage and at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze/thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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