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GPN1 / XAB1

GPN-loop GTPase 1

Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119).

Gene Name: GPN-loop GTPase 1
Family/Subfamily: Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806
Synonyms: GPN1, ATP(GTP)-binding protein, ATPBD1A, GPN-loop GTPase 1, MBD2-interacting protein, RPAP4, XPA binding protein 1, GTPase, MBDIN, NTPBP, XAB1, XPA binding protein 1, XPA-binding protein 1
Target Sequences: NM_007266 NP_009197.2 Q9HCN4

☰ Filters
Antibodies (17)
Proteins (8)
Over-Expression Lysate (4)
Primary (17)
Recombinant (4)
GPN1 / XAB1 (25)
Human (17)
Mouse (2)
Rat (1)
IHC (2)
IHC-P (2)
WB (16)
ELISA (9)
IF (2)
IP (5)
rabbit (15)
mouse (2)
Product Group
IHCPlus (1)
IgG (12)
IgG1 (1)
IgG1,k (1)
monoclonal mc (2)
polyclonal pc (15)
3E1 (1)
APC Conjugated (1)
Azide-free (2)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (12)
aa325-352 (7)
aa324-374 (1)
aa325-375 (1)
aa9-119 (1)
No (25)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (5)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (2)
GPN1 / XAB1 Antibody - Anti-GPN1 / XAB1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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GPN1 / XAB1 Mouse anti-Human Monoclonal (3E1) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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GPN1 / XAB1 Mouse anti-Human Monoclonal (aa9-119) (Azide-free) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated, Azide-free
100 µg/$705
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GPN1 / XAB1 Rabbit anti-Human Polyclonal (aa325-352) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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GPN1 / XAB1 Rabbit anti-Human Polyclonal (aa325-352) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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GPN1 / XAB1 Rabbit anti-Human Polyclonal (aa325-352) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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GPN1 / XAB1 Rabbit anti-Human Polyclonal (aa325-352) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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GPN1 / XAB1 Rabbit anti-Human Polyclonal (aa325-352) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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GPN1 / XAB1 Rabbit anti-Human Polyclonal (aa325-352) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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GPN1 / XAB1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
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GPN1 / XAB1 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$412
GPN1 / XAB1 Antibody - Detection of human GPN1 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-GPN1 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
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GPN1 / XAB1 Rabbit anti-Human Polyclonal (aa324-374) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
GPN1 / XAB1 Antibody - Detection of human and mouse GPN1 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-GPN1 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
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GPN1 / XAB1 Rabbit anti-Human Polyclonal (aa325-375) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
GPN1 / XAB1 Antibody - Anti-GPN1 rabbit polyclonal antibody at 1:500 dilution. Lane A: HL-60 Whole Cell Lysate. Lane B: HeLa Whole Cell Lysate. Lane C: U-251 MG Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 42 kDa. Observed band size: 44 kDa.
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GPN1 / XAB1 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$412
GPN1 / XAB1 Antibody - GPN1 Antibody western blot of 293 cell line lysates (35 ug/lane). The GPN1 antibody detected the GPN1 protein (arrow).
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GPN1 / XAB1 Rabbit anti-Human Polyclonal (aa325-352) Antibody
Human
WB
Unconjugated
400 µl/$393
GPN1 / XAB1 Antibody
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GPN1 / XAB1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
GPN1 / XAB1 Antibody - Western blot analysis of extracts of various cell lines, using GPN1 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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GPN1 / XAB1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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GPN1 / XAB1 Rabbit anti-Human Polyclonal Antibody
Human
IP
Unconjugated
100 µl/$749
GPN1 / XAB1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GPN1 / XAB1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
31.7 kDa
20 µg/$150
GPN1 / XAB1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
40.8 kDa
20 µg/$150
GPN1 / XAB1 Protein - Purified recombinant protein GPN1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
41.6 kDa
20 µg/$1,107
GPN1 / XAB1 Protein - 12.5% SDS-PAGE of human XAB1 stained with Coomassie Blue
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Wheat Germ Extract
GST
68.1 kDa
10 µg/$479; 25 µg/$670
GPN1 / XAB1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
40.8 kDa
100 µg/$494
GPN1 / XAB1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
31.7 kDa
100 µg/$494
GPN1 / XAB1 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-25 of 25 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).