Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
GPIHBP1 antibody was raised against a synthetic peptide within an internal region [residues 100-170] of the mouse GPI-anchored HDL-binding protein 1 protein. [Swiss-Prot# Q9D1N2]. Percent identity by BLAST analysis: Rat (86%).
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
GPIHBP1 is a capillary endothelial cell protein that facilitates the lipolytic processing of triglyceride-rich lipoproteins. The encoded protein is a glycosylphosphatidylinositol-anchored protein that is a member of the lymphocyte antigen 6 (Ly6) family. This protein plays a major role in transporting lipoprotein lipase (LPL) from the subendothelial spaces to the capillary lumen. Mutations in this gene are the cause of hyperlipoproteinemia, type 1D.
Detection of Gpihbp1 in transfected lysate (Lane 1). AN empty vector lysate was used as a negative control (Lane 2). This image was taken for the unconjugated form of this product. Other forms have not been tested.