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Anti-GPER1 / GPR30 Antibody (Extracellular Domain) IHC-plus™ LS-A4268

Note: This antibody replaces LS-C66913
Catalog Size Price
LS-A4268-50 50 µg (1 mg/ml) Unavailable
Same day shipping In Stock - Same day shipping

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30 GPER1 / GPR30 Antibodies

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Anti-GPER1 / GPR30 Antibody (aa275-288) LS-C313331
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100% Guaranteed In Stock
Rabbit Polyclonal to Human GPER1 / GPR30
Human
IHC - Paraffin, ELISA
Unconjugated

Details

Human GPER1 / GPR30
Rabbit
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 - 7.5 µg/ml)
  • ELISA

Specificity and Use

GPER1 / GPR30 antibody was raised against synthetic 15 amino acid peptide from 2nd extracellular domain of human GPR30. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%); Marmoset, Elephant (93%); Mouse, Rat, Hamster, Panda, Horse, Opossum, Platypus (87%); Dog, Bovine, Turkey, Zebra finch, Chicken (80%).
LS-E28930 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A4268. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Extracellular Domain
Human GPR30. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About GPER1 / GPR30

Q99527 NM_001505 NP_001496.1

GPER1 Antibody, CMKRL2 Antibody, CEPR Antibody, FEG-1 Antibody, G-protein coupled receptor 30 Antibody, G protein-coupled receptor 30 Antibody, GPCR-Br Antibody, GPER Antibody, Heptahelix receptor Antibody, LERGU Antibody, LyGPR Antibody, MER Antibody, GPR30 Antibody, IL8-related receptor DRY12 Antibody, LERGU2 Antibody, Chemokine receptor-like 2 Antibody, DRY12 Antibody, Membrane estrogen receptor Antibody

G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK.

Immunohistochemistry

Immunohistochemistry
Anti-GPR30 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A4268 dilution 5-7.5 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-GPR30 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A4268 dilution 5-7.5 ug/ml.

Requested From: 
Date Requested: 11/20/2017

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