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Anti-GPER1 / GPR30 Antibody (C-Terminus) IHC-plus™ LS-A4272

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
Inquire for larger quantities
Same day shipping In Stock - Same day shipping

LSBio (Direct) LSBio (Direct)
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Most Popular GPER1 / GPR30 Antibodies

Anti-GPER1 / GPR30 Antibody (Extracellular Domain) IHC-plus™ LS-A1184
Rabbit Polyclonal to Human GPER1 / GPR30
Human
IHC - Paraffin, Immunofluorescence
Unconjugated
Immunohistochemistry Image
Anti-GPER1 / GPR30 Antibody (Extracellular Domain) IHC-plus™ LS-A4271
Rabbit Polyclonal to Human GPER1 / GPR30
Human, Monkey
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-GPER1 / GPR30 Antibody (C-Terminus) IHC-plus™ LS-A4272
Rabbit Polyclonal to Human GPER1 / GPR30
Human, Monkey, Dog
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed In Stock In Stock Publications Publications (4)
Rabbit Polyclonal to Human GPER1 / GPR30
Human, Monkey, Dog
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated

Details

Human GPER1 / GPR30
Rabbit
Human, Monkey, Dog (tested or 100% immunogen sequence identity)
Rat, Horse (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 - 10 µg/ml)
  • Immunofluorescence
  • Western blot

Specificity and Use

GPER1 / GPR30 antibody was raised against synthetic 18 amino acid peptide from C-terminus of human GPR30. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Dog (100%); Rat, Horse (94%); Mouse, Hamster (89%); Elephant, Bovine (83%).
LS-E28933 - Liquid - 50 µg - $145.00
C-Terminus
Human GPR30. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

Publications (4)

1
Impaired leukocyte influx in cervix of postterm women not responding to prostaglandin priming. Sahlin L, Stjernholm-Vladic Y, Roos N, Masironi B, Ekman-Ordeberg G. Reproductive biology and endocrinology : RB&E. 2008 6:36. (IHC-P; Human) [Full Text Article] [PubMed:18764934] [PMC:PMC2551600]
2
Spinal synthesis of estrogen and concomitant signaling by membrane estrogen receptors regulate spinal - and -opioid receptor heterodimerization and female-specific spinal morphine antinociception. Liu NJ, Chakrabarti S, Schnell S, Wessendorf M, Gintzler AR. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 31:11836-45. (IHC-Fr; Rat) [Full Text Article] [PubMed:21849544] [PMC:PMC3321927]
3
Regulation of ERRalpha gene expression by estrogen receptor agonists and antagonists in SKBR3 breast cancer cells: differential molecular mechanisms mediated by g protein-coupled receptor GPR30/GPER-1. Li Y, Birnbaumer L, Teng CT. Molecular endocrinology (Baltimore, Md.). 2010 May;24:969-80. [Full Text Article] [PubMed:20211987] [PMC:PMC2870941]
4
Stallion spermatozoa: putative target of estrogens; presence of the estrogen receptors ESR1, ESR2 and identification of the estrogen-membrane receptor GPER. Arkoun B, Gautier C, Delalande C, Barrier-Battut I, Gu[Character e9]non I, Goux D, Boura[Character ef]ma-Lelong H. General and comparative endocrinology. 2014 May;200:35-43. [Full Text Article] [PubMed:24607572]
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About GPER1 / GPR30

Q99527 NM_001505 NP_001496.1

GPER1 Antibody, CMKRL2 Antibody, CEPR Antibody, FEG-1 Antibody, G-protein coupled receptor 30 Antibody, G protein-coupled receptor 30 Antibody, GPCR-Br Antibody, GPER Antibody, Heptahelix receptor Antibody, LERGU Antibody, LyGPR Antibody, MER Antibody, GPR30 Antibody, IL8-related receptor DRY12 Antibody, LERGU2 Antibody, Chemokine receptor-like 2 Antibody, DRY12 Antibody, Membrane estrogen receptor Antibody

G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK.

Immunohistochemistry

Immunohistochemistry
Anti-GPER1 / GPR30 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-GPER1 / GPR30 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-GPR30 antibody LS-A4272 IHC of human breast carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry - Paraffin

Immunohistochemistry - Paraffin
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry - Paraffin

Immunohistochemistry - Paraffin
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
 

Requested From: United States
Date Requested: 12/4/2016

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