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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GPBAR1 / TGR5 Antibody LS‑C47389
TGR5 antibody LS-C47389 is an unconjugated rabbit polyclonal antibody to TGR5 (GPBAR1) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C47389-100
100 µl
Unavailable

Popular GPBAR1 / TGR5 Products

Anti-GPBAR1 / TGR5 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human
Applications: IHC, IHC - Paraffin
Anti-GPBAR1 / TGR5 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human
Applications: IHC, IHC - Paraffin
Antibody
Species: Human
Applications: Flow Cytometry
Western blot of BG37/TGR5 in spleen lysate. Lane 1 shows pre-immune sera. Lane 2 shows antibody tested at 1:5000 on mouse spleen lysate.
Species: Human, Mouse, Rat
Applications: Western blot
Western blot of BG37/TGR5 in spleen lysate. Lane 1 shows pre-immune sera. Lanes 2, 3 and 4 show antibody tested on human (1:1000), mouse (1:5000) and rat (1:5000) spleen lysate, respectively.
Species: Human, Mouse, Rat
Applications: Western blot

Product Description

TGR5 antibody LS-C47389 is an unconjugated rabbit polyclonal antibody to TGR5 (GPBAR1) from human, mouse, rat and other species. Validated for WB.
About GPBAR1 / TGR5
GPBAR1 / TGR5 is a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Q8TDU6 AB083601 NP_733800.1

GPBAR1 Antibody, BG37 Antibody, GPR131 Antibody, HGPCR19 Antibody, M-BAR Antibody, GPCR19 Antibody, TGR5 Antibody, GPCR TGR5 Antibody, HBG37 Antibody, Membrane bile acid receptor Antibody


Specifications

Target
Human GPBAR1 / TGR5
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Modifications
Unmodified
Applications
  • Western blot (1:1000 - 1:5000)
Failed Applications
  • IHC - Paraffin
Immunogen
GPBAR1 / TGR5 antibody was raised against a portion of amino acid1-50of human BG37/TGR5.
Specificity
A portion of amino acid 1-50 of human BG37/TGR5.
Presentation
Sera, 50% glycerol, 0.025% sodium azide.
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of BG37/TGR5 in spleen lysate. Lane1 shows pre-immune sera. Lanes 2, 3 and 4 show antibody tested on human (1:1000), mouse (1:5000) and rat (1:5000) spleen lysate, respectively.
Western blot of BG37/TGR5 in spleen lysate. Lane1 shows pre-immune sera. Lanes 2, 3 and 4 show antibody tested on human (1:1000), mouse (1:5000) and rat (1:5000) spleen lysate, respectively.

Western blot

Western blot of BG37/TGR5 in spleen lysate. Lane1 shows pre-immune sera. Lanes 2, 3 and 4 show antibody tested on human (1:1000), mouse (1:5000) and rat (1:5000) spleen lysate, respectively.
Western blot of BG37/TGR5 in spleen lysate. Lane1 shows pre-immune sera. Lanes 2, 3 and 4 show antibody tested on human (1:1000), mouse (1:5000) and rat (1:5000) spleen lysate, respectively.

Western blot

Western blot of BG37/TGR5 in spleen lysate. Lane1 shows pre-immune sera. Lanes 2, 3 and 4 show antibody tested on human (1:1000), mouse (1:5000) and rat (1:5000) spleen lysate, respectively.
Western blot of BG37/TGR5 in spleen lysate. Lane1 shows pre-immune sera. Lanes 2, 3 and 4 show antibody tested on human (1:1000), mouse (1:5000) and rat (1:5000) spleen lysate, respectively.

Western blot

Western blot of BG37/TGR5 in spleen lysate. Lane1 shows pre-immune sera. Lanes 2, 3 and 4 show antibody tested on human (1:1000), mouse (1:5000) and rat (1:5000) spleen lysate, respectively.
Western blot of BG37/TGR5 in spleen lysate. Lane1 shows pre-immune sera. Lanes 2, 3 and 4 show antibody tested on human (1:1000), mouse (1:5000) and rat (1:5000) spleen lysate, respectively.


Requested From: 
Date Requested: 6/24/2018

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