Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Protein G purified
Western blot (1 - 2 µg/ml)
Flow Cytometry (25 µg/ml)
ELISA (0.5 - 1 µg/ml)
Specificity and Use
GP1BA / CD42b antibody was raised against nS0-derived rhGPIb-alpha. (aa 17 - 505).
Recognizes human GPIb-alpha.
Suitable for use in Flow Cytometry, Direct ELISA and Western Blot. Flow Cytometry: 25 ug/ml use 10 ul to label 1E6 cells. Direct ELISA: 0.5-1.0 ug/ml detection limit for rhGPIb-alpha is ~1 ng/well. Western Blot: 1-2 ug/ml detection limit for rhGPIb-alpha is ~5 ng/lane under non-reducing and reducing conditions.
Lyophilized from PBS, 5% trehalose. Reconstitute, 200 ul sterile 40-50% glycerol, PBS.
Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V.