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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GOK / STIM1 Antibody (aa600‑685) LS‑C49169
Note: This antibody replaces LS-C76131
STIM1 antibody LS-C49169 is an unconjugated rabbit polyclonal antibody to human STIM1 (GOK). Validated for WB.
Catalog
Size
Price
LS-C49169-100
100 µl
Unavailable

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Product Description

STIM1 antibody LS-C49169 is an unconjugated rabbit polyclonal antibody to human STIM1 (GOK). Validated for WB.
About GOK / STIM1
GOK / STIM1 is a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. Q13586 NM_003156 NP_003147.2

STIM1 Antibody, D11S4896E Antibody, Stromal interaction molecule 1 Antibody, GOK Antibody, STIM1L Antibody


Specifications

Target
Human GOK / STIM1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, DY650, DY488, DY550.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.5 - 2 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
GOK / STIM1 antibody was raised against a synthetic peptide made to a C-terminal region (within residues 600-685) of the human protein. [Uniprot# Q13586]. Percent identity by BLAST analysis: Porcine (93%); Xenopus (79%).
Epitope
aa600-685
Specificity
Stromal interaction molecule 1.
Presentation
PBS plus 30% glycerol, 0.1% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Detection of STIM-1 in HeLa WCE.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of STIM-1 in HeLa WCE. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of STIM-1 in HeLa WCE.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of STIM-1 in HeLa WCE. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of STIM-1 in HeLa WCE.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of STIM-1 in HeLa WCE. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of STIM-1 in HeLa WCE.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of STIM-1 in HeLa WCE. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/25/2018

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