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GLUL / Glutamine Synthetase

glutamate-ammonia ligase

GLUL / Glutamine Synthetase belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.

Gene Name: glutamate-ammonia ligase
Synonyms: GLUL, GLNS, Glutamate decarboxylase, Glutamate-ammonia ligase, Glutamine synthase, GS, Glutamate--ammonia ligase, Glutamine synthetase, PIG43, PIG59
Target Sequences: NM_002065 NP_002056.2 P15104

Publications (3)

1
GLUL Ablation Can Confer Drug Resistance to Cancer Cells via a Malate-Aspartate Shuttle-Mediated Mechanism. Magesh Muthu, Ranjeet Kumar, Azharuddin Sajid Syed Khaja, Jonathan D Gilthorpe, Jenny L Persson, Anders Nordström. Cancers. 2019 Dec;11:1945. [Full Text Article] [PubMed:31817360] [PMC:PMC6966511] Related Antibodies: LS-C114787.
2
Toll-Like Receptor 9-Mediated Neuronal Innate Immune Reaction Is Associated with Initiating a Pro-Regenerative State in Neurons of the Dorsal Root Ganglia Non-Associated with Sciatic Nerve Lesion. Petr Dubový, Ivana Hradilová-Svíženská, Václav Brázda, Marek Joukal. International journal of molecular sciences. 2021 July;22:7446. [Full Text Article] [PubMed:34299065] [PMC:PMC8304752] Related Antibodies: LS-B2579.
3
Bilateral elevation of interleukin-6 protein and mRNA in both lumbar and cervical dorsal root ganglia following unilateral chronic compression injury of the sciatic nerve. Dubov[Character fd] P, Br[Character e1]zda V, Klus[Character e1]kov[Character e1] I, Hradilov[Character e1]-Sv[Character ed]ensk[Character e1] I. Journal of neuroinflammation. 2013 10:55. [Full Text Article] [PubMed:23634725] [PMC:PMC3657546] Related Antibodies: LS-B2579.

☰ Filters
Antibodies (80)
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GLUL / Glutamine Synthetase (111)
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GLUL / Glutamine Synthetase Antibody - Anti-GLUL / Glutamine Synthetase antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Cancer Pathology
Cancer
GLUL / Glutamine Synthetase Mouse anti-Sheep Monoclonal (GS-6) Antibody
Sheep, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$545
GLUL / Glutamine Synthetase Antibody - Anti-GLUL / Glutamine Synthetase antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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GLUL / Glutamine Synthetase Rabbit anti-Rat Polyclonal Antibody
Mouse, Bovine, Rat, Human
IF, IHC, IHC-P, IHC-Pfa, WB
Unconjugated
0.1 ml/$460
GLUL / Glutamine Synthetase Antibody - Immunohistochemical staining of paraffin-embedded breast tissue using anti-GLUL mouse monoclonal antibody. (Dilution 1:50).
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GLUL / Glutamine Synthetase Mouse anti-Human Monoclonal (OTI1F4) Antibody
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
GLUL / Glutamine Synthetase Antibody - Immunohistochemical staining of paraffin-embedded breast tissue using anti-GLUL mouse monoclonal antibody. (Dilution 1:50).
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GLUL / Glutamine Synthetase Mouse anti-Human Monoclonal (Carrier-free) (OTI1F4) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
GLUL / Glutamine Synthetase ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
0.27 - 200 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$990
GLUL / Glutamine Synthetase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$854
GLUL / Glutamine Synthetase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$893
GLUL / Glutamine Synthetase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
GLUL / Glutamine Synthetase Antibody - Human Breast Adipocytes: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
GLUL / Glutamine Synthetase Mouse anti-Human Monoclonal (AT8D7) Antibody
Human
ELISA, ICC, IF, IHC-P, WB
Unconjugated
100 µl/$460
GLUL / Glutamine Synthetase Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Cancer Pathology
Cancer
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal (aa301-350) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
GLUL / Glutamine Synthetase Antibody - Anti-GLUL / Glutamine Synthetase antibody IHC of human colon, submucosal plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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Cancer Pathology
Cancer
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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E. coli
His
44.5 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
GLUL / Glutamine Synthetase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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GLUL / Glutamine Synthetase Rabbit anti-Bovine Polyclonal Antibody
Mouse, Bovine, Rat
IHC, WB
Unconjugated
100 µl/$649
GLUL / Glutamine Synthetase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal (aa70-96) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
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GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal (aa70-96) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
GLUL / Glutamine Synthetase Antibody - Immunohistochemistry of paraffin-embedded human glioma cancer at dilution of 1:100
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GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
GLUL / Glutamine Synthetase Antibody - 1:100 staining mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$341
Select
E. coli
His
44.3 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
GLUL / Glutamine Synthetase Protein - 12.5% SDS-PAGE of human GLUL stained with Coomassie Blue
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Wheat Germ Extract
GST
66.77 kDa
10 µg/$479; 25 µg/$670
GLUL / Glutamine Synthetase Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$412
GLUL / Glutamine Synthetase Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using GLUL Polyclonal Antibody at dilution of 1:60.
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GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Viewing 1-25 of 111 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).