Rat, Human, Mouse
(tested or 100% immunogen sequence identity)
- IHC - Frozen (1:1000)
- Western blot (1:1000)
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GLRA1/GLRA2 antibody was raised against synthetic peptide corresponding to the N-terminal region of rat glycine receptor alpha 1 subunit. ( N-TERMINAL ).
Recognizes an epitope within the N-terminal region (NT) of glycine receptor alpha 1 and alpha 2 subunits. Glycine receptors are members of the ligand-gated ion channel superfamily, which mediate fast inhibitory neurotransmission. The receptors are pentameric membrane proteins which form chloride channels. Binding of glycine to its receptor produces an increase in chloride conductance and membrane hyperpolarisation. Four genes encoding glycine receptor alpha subunits have been identified, together with a single beta polypeptide. Each subunit consists of a large extracellular N-terminal region, four transmembrane domains, and a large cytoplasmic domain.
Western Blot: LS-C43103 detects a band of approximately 48 kD in rat spinal cord lysates.
100 µl PBS
For research use only.
This antibody carries the LSBio 100% Guarantee.