GLI3

GLI family zinc finger 3

Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in regulating the size of the zone of distal chondrocytes, in restricting the zone of PTHLH expression in distal cells and in activating chondrocyte proliferation. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.

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Products

Antibodies (25)

Proteins (3)

ELISA Kits (1)

Type

Primary (25)

Recombinant (3)

Sandwich (1)

Target

GLI3 (29)

Reactivity

Human (18)

Mouse (13)

Rat (5)

Bat (1)

Bovine (1)

Chicken (3)

Chimpanzee (1)

Dog (2)

Hamster (1)

Horse (1)

Monkey (1)

Pig (1)

Quail (1)

Rabbit (2)

Squirrel monkey (1)

Xenopus (1)

Xenopus laevis (1)

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Application

IHC (5)

IHC-P (2)

WB (21)

Flo (1)

ELISA (6)

ICC (1)

IF (6)

IP (1)

Peptide-ELISA (2)

Host

rabbit (22)

mouse (1)

goat (2)

Product Group

IHCPlus (1)

Isotype

IgG (6)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (24)

Clone

2C9 (1)

Format

96-Well Microplate (1)

APC (2)

APC Conjugated (2)

Biotin Conjugated (2)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Unconjugated (11)

Epitope

aa111-343 (8)

aa303-561 (8)

30-110 aa, N-terminal (1)

aa11-60 (1)

aa40-57 (1)

aa431-442 (1)

Publications

No (29)

Sample Type

Cell Culture Supernatants (1)

Plasma (1)

Serum (1)

Tag

GST, N-terminus (1)

His-T7 (2)

Species

Human (2)

Mouse (1)

Source

E. coli (2)

Wheat Germ Extract (1)

Select

IHC-plus™ GLI3 Antibody LS-B73

(4.0) Rating

Antibody:

GLI3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Xenopus laevis, Quail, Chicken, Dog, Human, Chimpanzee, Squirrel monkey

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$515

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GLI3 Antibody (aa303-561) LS-C294190

Antibody:

GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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GLI3 Antibody (aa303-561, HRP) LS-C714238

Antibody:

GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

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GLI3 Antibody (aa303-561, Biotin) LS-C689197

Antibody:

GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

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GLI3 Antibody (aa303-561, FITC) LS-C696288

Antibody:

GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

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GLI3 Antibody (aa303-561, PE) LS-C728308

Antibody:

GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

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GLI3 Antibody (aa303-561, Cy3) LS-C705223

Antibody:

GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

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GLI3 Antibody (aa303-561, APC, Cy7) LS-C737213

Antibody:

GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781

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GLI3 Antibody (aa303-561, APC) LS-C719388

Antibody:

GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• Cy3
• APC, Cy7
• More...
  • APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • Cy3
  • APC, Cy7
  • APC

Select

GLI3 Antibody LS-C754748

Antibody:

GLI3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

GLI3 Antibody (aa431-442) LS-C54916

Antibody:

GLI3 Goat anti-Human Polyclonal (aa431-442) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Pig, Horse, Bat, Human

Applications:

Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$401

Select

GLI3 Antibody (aa11-60) LS-C199001

Antibody:

GLI3 Rabbit anti-Human Polyclonal (aa11-60) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

GLI3 Antibody (30-110 aa, N-terminal) LS-C383698

Antibody:

GLI3 Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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GLI3 Antibody LS-C822576

Antibody:

GLI3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

100 µg/$357

Select

GLI3 Antibody (clone 2C9) LS-C197308

Antibody:

GLI3 Mouse anti-Human Monoclonal (2C9) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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GLI3 Antibody LS-C36438

Antibody:

GLI3 Goat anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, ICC, WB

Format:

Unconjugated

Price:

100 µg/$962

Select

GLI3 Antibody (aa111-343) LS-C294189

Antibody:

GLI3 Rabbit anti-Human Polyclonal (aa111-343) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

Select

GLI3 Antibody (aa111-343, HRP) LS-C714234

Antibody:

GLI3 Rabbit anti-Human Polyclonal (aa111-343) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593

Select

GLI3 Antibody (aa111-343, Biotin) LS-C689198

Antibody:

GLI3 Rabbit anti-Human Polyclonal (aa111-343) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

Select

GLI3 Antibody (aa111-343, FITC) LS-C696285

Antibody:

GLI3 Rabbit anti-Human Polyclonal (aa111-343) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

Select

GLI3 Antibody (aa111-343, PE) LS-C728306

Antibody:

GLI3 Rabbit anti-Human Polyclonal (aa111-343) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

Select

GLI3 Antibody (aa111-343, Cy3) LS-C705220

Antibody:

GLI3 Rabbit anti-Human Polyclonal (aa111-343) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

Select

GLI3 Antibody (aa111-343, APC, Cy7) LS-C737211

Antibody:

GLI3 Rabbit anti-Human Polyclonal (aa111-343) (APC, Cy7) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676

Select

GLI3 Antibody (aa111-343, APC) LS-C719384

Antibody:

GLI3 Rabbit anti-Human Polyclonal (aa111-343) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• Cy3
• APC, Cy7
• More...
  • APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • Cy3
  • APC, Cy7
  • APC

Select

GLI3 Antibody (aa40-57) LS-C312915

Antibody:

GLI3 Rabbit anti-Human Polyclonal (aa40-57) Antibody

Reactivity:

Xenopus, Chicken, Rabbit, Rat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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