Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
GLI2 Antibody, GLI-Kruppel family member GLI2 Antibody, HPE9 Antibody, Gli-2 Antibody, Oncogene GLI2 Antibody, Tax helper protein 2 Antibody, THP Antibody, Zinc finger protein GLI2 Antibody, Tax helper protein Antibody, THP2 Antibody, GLI family zinc finger 2 Antibody, Tax helper protein 1 Antibody, THP1 Antibody
GLI2 is a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell.
GLI-2 in Mouse Embryo. GLI-2 was detected in immersion fixed frozen sections of mouse embryo (15 d. p. c.) using Goat Anti-Mouse GLI-2 Antigen Affinity-purified Polyclonal Antibody at 15 ug/ml overnight at 4°C. Tissue was stained using Anti-Goat HRP-DAB (brown) and counterstained with hematoxylin (blue). Lower panel shows a lack of labeling when primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents. Specific staining was localized to developing muscle.
Requested From: United States
Date Requested: 1/24/2017