Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
GLI2 Antibody, GLI-Kruppel family member GLI2 Antibody, HPE9 Antibody, Gli-2 Antibody, Oncogene GLI2 Antibody, Tax helper protein 2 Antibody, THP Antibody, Zinc finger protein GLI2 Antibody, Tax helper protein Antibody, THP2 Antibody, GLI family zinc finger 2 Antibody, Tax helper protein 1 Antibody, THP1 Antibody
GLI2 is a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell.
GLI-2 in Mouse Embryo. GLI-2 was detected in immersion fixed frozen sections of mouse embryo (15 d. p. c.) using Goat Anti-Mouse GLI-2 Antigen Affinity-purified Polyclonal Antibody at 15 ug/ml overnight at 4°C. Tissue was stained using Anti-Goat HRP-DAB (brown) and counterstained with hematoxylin (blue). Lower panel shows a lack of labeling when primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents. Specific staining was localized to developing muscle.