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Anti-GJC2 Antibody (C-Terminus) LS-C22366

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Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml Unavailable

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100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1,k) to Mouse GJC2
Mouse
Immunofluorescence, Western blot, Immunoprecipitation (applications tested for the base form of this product only)
Unconjugated

Details

Mouse GJC2
Mouse
Mouse (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750, PE.
Protein A purified
Unmodified

Applications

  • Immunofluorescence (1 - 3 µg/ml)
  • Western blot (1 - 3 µg/ml)
  • Immunoprecipitation (5 - 10 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

GJC2 antibody was raised against synthetic peptide derived from the C-terminal region of the mouse Connexin 47 protein.
C-Terminus
Reacts with the mouse Connexin 47 protein. On Western blots of mouse thalamus homogenates and Connexin 47-transfected HeLa cells, it identified a band at ~47kD. Reactivity was confirmed in Western blots with mouse thalamus lysates. Mouse Connexin 47-transfected HeLa cells were used in both Immunoprecipitation and Western blot assays. This antibody was also used in immunofluorescence assays using paraformaldehyde-fixed mouse brain. The expected staining pattern is punctate labeling of the oligodendrocytes in the brain.
Suitable for use in Immunofluorescence, Western Blot, Immunoprecipitation. Immunofluorescence: 1-3 ug/ml. Western Blot: 1-3 ug/ml. Immunoprecipitation: 5-10 ug/ml.

Packaging

PBS, pH 7.4, 0.1% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About GJC2

Q5T442 NM_020435 NP_065168.2

GJC2 Antibody, Cx47 Antibody, Connexin-46.6 Antibody, Connexin-47 Antibody, CX46.6 Antibody, Gap junction protein alpha 12 Antibody, GJA12 Antibody, Gap junction gamma-2 protein Antibody, LMPH1C Antibody, Gap junction alpha-12 protein Antibody, HLD2 Antibody, PMLDAR Antibody, SPG44 Antibody

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems.

Requested From: 
Date Requested: 3/27/2017

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