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Anti-GJA1 / CX43 / Connexin 43 Antibody (C-Terminus) LS-C14563

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Rabbit Polyclonal (IgG) to Mouse GJA1 / CX43 / Connexin 43
Mouse
Western blot, ELISA
Unconjugated

Details

Mouse GJA1 / CX43 / Connexin 43
Rabbit
Mouse (tested or 100% immunogen sequence identity)
Rat, Bovine (at least 90% immunogen sequence identity)
IgG Polyclonal
Unpurified serum

Applications

Western blot (1:1000 - 1:5000), ELISA (1:10000 - 1:100000)

Specificity and Use

GJA1 / CX43 / Connexin 43 antibody was raised against synthetic peptide corresponding to a 19 amino acid C-terminal peptide sequence within the cytoplasmic domain of mouse Cx43 (KLH conjugated).
C-Terminus
Recognizes mouse Cx43. No significant homology is seen with other connexins. Species sequence homology: Rat and bovine: 100%; chicken and human: 84%, (16/19 aa).
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:5000. Detects a band at ~43kD Cx43 in heart and other tissues. Higher MW bands may also be detected depending upon the samples. ELISA: 1:10000-1:100000 using 50-100 ng Cx43A control peptide/well.

Packaging

Neat serum, 40% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About GJA1 / CX43 / Connexin 43

P17302 NM_000165 NP_000156.1

GJA1 Antibody, Connexin-43 Antibody, DFNB38 Antibody, Connexin 43 Antibody, Gap junction alpha-1 protein Antibody, GJAL Antibody, HSS Antibody, Gap junction protein alpha 1 Antibody, ODDD Antibody, ODD Antibody, AVSD3 Antibody, CX43 Antibody, HLHS1 Antibody, ODOD Antibody, SDTY3 Antibody

Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development.

Requested From: United States
Date Requested: 4/24/2015

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