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Anti-GJA1 / CX43 / Connexin 43 Antibody (C-Terminus) LS-C14563

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Rabbit Polyclonal (IgG) to Mouse GJA1 / CX43 / Connexin 43
Mouse
Western blot, ELISA
Unconjugated

Details

Mouse GJA1 / CX43 / Connexin 43
Rabbit
Mouse (tested or 100% immunogen sequence identity)
Rat, Bovine (at least 90% immunogen sequence identity)
IgG Polyclonal
Unpurified serum

Applications

Western blot (1:1000 - 1:5000), ELISA (1:10000 - 1:100000)

Specificity and Use

GJA1 / CX43 / Connexin 43 antibody was raised against synthetic peptide corresponding to a 19 amino acid C-terminal peptide sequence within the cytoplasmic domain of mouse Cx43 (KLH conjugated).
C-Terminus
Recognizes mouse Cx43. No significant homology is seen with other connexins. Species sequence homology: Rat and bovine: 100%; chicken and human: 84%, (16/19 aa).
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:5000. Detects a band at ~43kD Cx43 in heart and other tissues. Higher MW bands may also be detected depending upon the samples. ELISA: 1:10000-1:100000 using 50-100 ng Cx43A control peptide/well.

Packaging

Neat serum, 40% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About GJA1 / CX43 / Connexin 43

P17302 NM_000165 NP_000156.1

GJA1 Antibody, Connexin-43 Antibody, DFNB38 Antibody, Connexin 43 Antibody, Gap junction alpha-1 protein Antibody, GJAL Antibody, HSS Antibody, Gap junction protein alpha 1 Antibody, ODDD Antibody, ODD Antibody, AVSD3 Antibody, CX43 Antibody, HLHS1 Antibody, ODOD Antibody, SDTY3 Antibody

Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.

Requested From: United States
Date Requested: 7/29/2015

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