Human GH / Growth Hormone

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

GhB9

Unconjugated

Affinity purified

Unmodified

Purified recombinant human growth hormone.

Recognizes human growth hormone (hGH), a 22kD polypeptide synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. It is also referred to as somatotropin. Many different isoforms exist in humans, from monomers to pentamers, disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. Human GH binds to two GH receptors and induces signal transduction through receptor dimerization. Growth hormone plays an important role in growth and cell production. An excess of GH results in acromegaly or gigantism, characterized by excessive growth. It can also be accompanied by muscle weakness, insulin resistance and pressure on nerves. Deficiency of GH may result in lack of strength, energy and bone mass. May be used to detect human growth hormone in ELISA assays.

• ELISA

ELISA: This product may be used in an indirect ELISA

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P01241 NCBI: NM_000515 NP_000506.2