Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 138H11] (IgG1) to Human GGT1 / GGT
IHC, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Human GGT1 / GGT
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [138H11]
Protein G purified
IHC - Frozen
Specificity and Use
GGT1 / GGT antibody was raised against purified human kidney gGT. Cellular Localization: Cell membrane.
Recognizes Human Glutamyl Transferase, gamma (Mr 90kD). Does not react with porcine or bovine.
Suitable for use in Flow Cytometry, Immunoprecipitation, Immunohistochemistry and Western Blot. Immunohistochemistry: Frozen only. Positive control: CaKi renal tumor cells. Renal cell carcinoma or kidney.
10 mM PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases.