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Anti-GFRA2 Antibody LS-C150113


Wt. Vol. Conc. Price
100 µg - - Unavailable

Most Popular GFRA2 Antibodies

Anti-GFRA2 Antibody LS-C149958
Goat Polyclonal (IgG) to Human GFRA2
IHC, Western blot, ELISA
Anti-GFRA2 Antibody LS-C150113
Goat Polyclonal (IgG) to Human GFRA2
IHC - Frozen, Western blot, ELISA
Anti-GFRA2 Antibody (aa117-314, Biotin) LS-C421716
Rabbit Polyclonal (IgG) to Human GFRA2
IHC - Paraffin, IHC - Frozen, ICC, Western blot, ELISA
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Human GFRA2
IHC - Frozen, Western blot, ELISA


Human GFRA2
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • IHC - Frozen
  • Western blot (0.1 - 0.2 µg/ml)

Specificity and Use

GFRA2 antibody was raised against nS0-derived rmGFRa-2 extracellular domain.
Mouse GFRa-2, human GFRa-2.
Blockade of receptor-ligand interaction-Approximately 1-3 µg/ml of this antibody will block 50% of the binding of 2 ng/ml rhGDNF to immobilized rmGFRa-2/Fc Chimera (100 ul of a 1 µg/ml solution was coated in each well) in a functional ELISA assay. Western blot-This antibody can be used at 0.1-0.2 µg/ml with the appropriate secondary reagents to detect mouse and human GFRa-2. The detection limit for rmGFRa-2 and rhGFRa-2 is approximately 5 ng/lane under non-reducing and reducing conditions. Immunohistochemistry-This antibody will label GFRa-2 receptors in frozen rat tissue sections (i. e. spinal cord and dorsal root ganglia). The working dilution is. 2-15 µg/ml. Direct ELISA-This antibody can be used at 0.5-1.0 µg/ml with the appropriate secondary reagents to detect mouse and human GFRa-2. The detection limit for rmGFRa-2 and rhGFRa-2 is approximately 1.5 ng/well. Note: GFRa-2 is a fixation-sensitive protein. Prolonged post-fixation with paraformaldehyde may reduce or abolish tissue labeling.


Lyophilized from 0.2 um filtered solution in PBS, 5% trehalose
Reconstitute at 0.2 mg/mL in sterile PBS
Store at -20°C.
For research use only.

About GFRA2

O00451 NM_001495 NP_001486.4

GFRA2 Antibody, GDNF receptor alpha-2 Antibody, GDNFRB Antibody, GFR-alpha 2 Antibody, GFR-alpha-2 Antibody, GDNF family receptor alpha-2 Antibody, GDNFR-beta Antibody, GDNF family receptor alpha 2 Antibody, Neurturin receptor alpha Antibody, RET ligand 2 Antibody, TRNR2 Antibody, TRN receptor, GPI-anchored Antibody, NTNR-alpha Antibody, NTNRA Antibody, GDNF receptor beta Antibody, GDNFR-alpha-2 Antibody, NRTNR-ALPHA Antibody, RETL2 Antibody

Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN), play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRa, which is a cell surface receptor for NTN. The cDNAs encoding NTNRa from human, rat, chicken, and mouse have been cloned recently (2-7).

Requested From: 
Date Requested: 3/24/2017

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