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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GFRA2 Antibody (aa376‑390) LS‑C66500
Antibody
GFRA2 antibody LS-C66500 is an unconjugated rabbit polyclonal antibody to GFRA2 from human, mouse, rat and other species. Validated for IHC and WB.
Catalog
Size
Price
LS-C66500-100
100 µl
Unavailable

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Product Description

GFRA2 antibody LS-C66500 is an unconjugated rabbit polyclonal antibody to GFRA2 from human, mouse, rat and other species. Validated for IHC and WB.
About GFRA2
Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN), play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRa, which is a cell surface receptor for NTN. The cDNAs encoding NTNRa from human, rat, chicken, and mouse have been cloned recently (2-7). O00451 NM_001495 NP_001486.4

GFRA2 Antibody, GDNF receptor alpha-2 Antibody, GDNFRB Antibody, GFR-alpha 2 Antibody, GFR-alpha-2 Antibody, GDNF family receptor alpha-2 Antibody, GDNFR-beta Antibody, GDNF family receptor alpha 2 Antibody, Neurturin receptor alpha Antibody, RET ligand 2 Antibody, TRNR2 Antibody, TRN receptor, GPI-anchored Antibody, NTNR-alpha Antibody, NTNRA Antibody, GDNF receptor beta Antibody, GDNFR-alpha-2 Antibody, NRTNR-ALPHA Antibody, RETL2 Antibody


Specifications

Target
Human GFRA2
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Dog, Hamster, Horse, Pig (tested or 100% immunogen sequence identity)
Predicted
Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • IHC
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GFRA2 antibody was raised against a synthetic peptide (PRVEKTPSLPDDLSD) as a part of human GFR alpha-2 protein (aa: 376-390) conjugated to KLH. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Dog, Bat, Horse, Pig (100%); Orangutan, Elephant, Bovine (93%); Opossum, Platypus (87%).
Epitope
aa376-390
Specificity
Western blot analysis indicates a high level of specificity to GFR alpha-2 for this antiserum. Species cross-reactivity: This antibody is known to react with rat GFR alpha-2.
Usage
Suitable for use in Western Blot and Immunohistochemistry.
Presentation
Lyophilized powder. Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.
Reconstitution
100 µl Reconstitute with ddH2O.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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