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GFRA1 / GFR Alpha

GDNF family receptor alpha 1

Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRa, which is a cell surface receptor for GDNF. The cDNAs encoding GDNFRa from human, rat, chicken and mouse have been cloned recently. GDNFRa was also termed Ret ligand 1 (RETL1) or TGF-b-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRa-1 recently. GFRa-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFRa and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function.

Gene Name: GDNF family receptor alpha 1
Family/Subfamily: GDNF Receptor , Not assigned-Other
Synonyms: GFRA1, GDNF receptor alpha-1, GDNFRA, GFR-ALPHA-1, GDNF family receptor alpha-1, GDNFR, GDNFR-alpha-1, RET ligand 1, RETL1, TRNR1, RET1L, GDNF family receptor alpha 1, GPI-linked anchor protein
Target Sequences: NM_005264 NP_005255.1 P56159

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Antibodies (43)
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GFRA1 / GFR Alpha (76)
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GFRA1 / GFR Alpha Antibody - Immunohistochemistry of GFRa-1 in human brain tissue with GFRa-1 antibody at 1 µg/ml.
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
GFRA1 / GFR Alpha Antibody - Immunofluorescence analysis of U20S cell using GFRA1 antibody. Blue: DAPI for nuclear staining.
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
GFRA1 / GFR Alpha ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
GFRA1 / GFR Alpha Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using GFRA1 Antibody at dilution of 1:100
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
GFRA1 / GFR Alpha Antibody - Immunofluorescence of monoclonal antibody to GFRA1 on HeLa cell . [antibody concentration 10 ug/ml]
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GFRA1 / GFR Alpha Mouse anti-Human Monoclonal (1G4) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
GFRA1 / GFR Alpha Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal (aa239-350) Antibody
Pig, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
GFRA1 / GFR Alpha Antibody - Immunohistochemistry - Anti-GFRA1/Gfr Alpha 1 Picoband Antibody
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
GFRA1 / GFR Alpha Antibody - Immunohistochemistry of paraffin-embedded Human brain tissue  using GFRA1 Polyclonal Antibody at dilution of 1:65(×200)
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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GFRA1 / GFR Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, IHC-P
Unconjugated
20 µl/$271; 100 µl/$412
GFRA1 / GFR Alpha Antibody - IHC-P: GFRA1 antibody testing of human lung cancer tissue
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal (aa25-227) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
GFRA1 / GFR Alpha Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal (30-110 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GFRA1 / GFR Alpha Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GFR alpha-1 Antibody. The picture on the right is blocked with the synthesized peptide.
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal (aa51-100) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
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GFRA1 / GFR Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µl/$412
GFRA1 / GFR Alpha Antibody - Immunofluorescence analysis of U2OS cells using GFRA1 Polyclonal Antibody.
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
GFRA1 / GFR Alpha Antibody - IHC of GFR -1 (K90) pAb in paraffin-embedded human brain tissue.
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal (Lys90) Antibody
Mouse, Rat, Human
IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
GFRA1 / GFR Alpha Antibody - Western blot analysis of 293T cell, using GFRA1 Polyclonal Antibody at dilution of 1:1250.
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Rat, Human
IHC, WB
HRP Conjugated
100 µl/$1,006
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Rat, Human
IHC, WB
Biotin Conjugated
100 µl/$1,006
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Rat, Human
IHC, WB
FITC Conjugated
100 µl/$1,006
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Rat, Human
IHC, WB
PE Conjugated
100 µl/$1,006
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GFRA1 / GFR Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
GFRA1 / GFR Alpha Antibody - Immunofluorescence analysis of U2OS cells using GFRA1 Polyclonal Antibody at dilution of 1:100.Blue: DAPI for nuclear staining.
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GFRA1 / GFR Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
GFRA1 / GFR Alpha Antibody - Western blot of GFRA1 / GFR Alpha antibody.
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GFRA1 / GFR Alpha Rabbit anti-Mouse Polyclonal (aa239-350) Antibody
Mouse
WB
Unconjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
GFRA1 / GFR Alpha Antibody - Western blot of GFRA1 / GFR Alpha antibody.
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GFRA1 / GFR Alpha Rabbit anti-Mouse Polyclonal (aa239-350) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$333; 200 µl/$385; 500 µl/$559; 1 ml/$671; 2 ml/$907; 5 ml/$1,525
Viewing 1-25 of 76 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).