Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Protein G purified from tissue culture supernatant
(applications tested for the base form of this product only)
Specificity and Use
GFAP antibody was raised against synthetic peptide; amino acids 411-422 (KTVEMRDGEVIK) of human GFAP (accession # P14136); 100% identical in rat and mouse. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Mouse, Rat, Ferret, Bovine, Bat, Hamster, Elephant, Panda, Rabbit, Horse, Pig, Guinea pig (100%).
Detects a 50kD protein in WB. Does not cross-react with GFAP-R416W or other proteins (based on KO validation results).
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.