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Geminin

geminin, DNA replication inhibitor

Geminin is a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.

Gene Name: geminin, DNA replication inhibitor
Synonyms: GMNN, Geminin
Target Sequences: NM_015895 NP_056979.1 O75496

☰ Filters
Antibodies (48)
Proteins (9)
ELISA Kits (2)
Custom (2)
Over-Expression Lysate (2)
Primary (48)
Recombinant (7)
Geminin (59)
Human (33)
Mouse (12)
Rat (11)
IHC (20)
IHC-P (6)
WB (43)
Flo (1)
ELISA (16)
IF (1)
IP (3)
Peptide-ELISA (1)
SDS-PAGE (1)
rabbit (45)
mouse (3)
Product Group
IHCPlus (1)
IgG (18)
IgG1,k (3)
monoclonal mc (3)
polyclonal pc (45)
1A8 (1)
2H7 (1)
96-Well Strip Plate (2)
APC (3)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (19)
aa1-206 (8)
aa1-209 (8)
aa8-206 (8)
aa96-123 (7)
aa50-100 (2)
N-Terminus (1)
aa160-C-term (1)
No (59)
GST (1)
GST, N-terminus (1)
His (1)
His-GST (2)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (6)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
Geminin Antibody - Anti-GMNN / Geminin antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 1 ug/ml.
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Geminin Mouse anti-Human Monoclonal (1A8) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Geminin Antibody - The 293T cell lysates(50 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human Geminin (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
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Geminin Mouse anti-Human Monoclonal (2H7) Antibody
Human
ELISA, SDS-PAGE, WB
Unconjugated
50 µl/$303; 100 µl/$365
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Geminin Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$459; 100 µl/$688
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Geminin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, IP, WB
Unconjugated
100 µg/$331
Geminin Protein
Select
E. coli
His
100 µg/$411; 500 µg/$985; 20 µg/$276
Geminin Antibody - Detection of Human Geminin by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-Geminin used at a dilution of 1:5000 (0.2 Detection: DAB.
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Geminin Rabbit anti-Human Polyclonal (aa160-C-term) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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Geminin Rabbit anti-Human Polyclonal (aa96-123) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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Geminin Rabbit anti-Human Polyclonal (aa96-123) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
Geminin Rabbit anti-Human Polyclonal (aa96-123) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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Geminin Rabbit anti-Human Polyclonal (aa96-123) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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Geminin Rabbit anti-Human Polyclonal (aa96-123) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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Geminin Rabbit anti-Human Polyclonal (aa96-123) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Geminin Antibody - Immunohistochemistry of paraffin-embedded human liver cancer using GMNN antibody at dilution of 1:200 (200x lens).
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Geminin Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Geminin Antibody - Immunohistochemistry of paraffin-embedded human testis tissue using antibody at dilution of 1:100.
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Geminin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
Geminin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
Geminin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
Geminin Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
50 µg/$294; 100 µg/$360
Geminin Antibody - GMNN Antibody (Center Y111) IHC of formalin-fixed and paraffin-embedded lung carcinoma tissue followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of the GMNN Antibody (Center Y111) for immunohistochemistry.
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Geminin Rabbit anti-Human Polyclonal (aa96-123) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Geminin Antibody - Immunohistochemical analysis of Geminin staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Geminin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
Geminin Antibody - 1:100 staining rat lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Geminin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Geminin Antibody - Detection of Human Geminin by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-Geminin used at a dilution of 1:5000 (0.2 Detection: DAB.
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Geminin Rabbit anti-Human Polyclonal (aa50-100) Antibody
Human
IHC, IHC-P, IP
Unconjugated
10 µg/$295; 100 µl/$514
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Geminin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
Geminin Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
Geminin Rabbit anti-Human Polyclonal (aa50-100) Antibody
Human
ELISA, WB
Unconjugated
40 µg/$485
Select
Geminin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
40 µg/$485
Viewing 1-25 of 59 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).