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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GDF9 / GDF‑9 Antibody (Glu322) LS‑C177281
GDF-9 antibody LS-C177281 is an unconjugated rabbit polyclonal antibody to human GDF-9 (GDF9). Validated for IHC and WB.
Catalog
Size
Price
LS-C177281-100
100 µl
Unavailable

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Product Description

GDF-9 antibody LS-C177281 is an unconjugated rabbit polyclonal antibody to human GDF-9 (GDF9). Validated for IHC and WB.
About GDF9 / GDF-9
Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. O60383 NM_005260 NP_005251.1

GDF9 Antibody, GDF-9 Antibody


Specifications

Target
Human GDF9 / GDF-9
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GDF9 / GDF-9 antibody was raised against synthetic peptide around Glu322 of human GDF9
Epitope
Glu322
Specificity
Human GDF9
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of GDF-9 (E322)pAb in paraffin-embedded human liver carcinoma tissue.
IHC of GDF-9 (E322)pAb in paraffin-embedded human liver carcinoma tissue.

Western blot

Western blot of GDF-9 (E322) pAb in extracts from COLO205 cells.
Western blot of GDF-9 (E322) pAb in extracts from COLO205 cells.

Immunohistochemistry

IHC of GDF-9 (E322)pAb in paraffin-embedded human liver carcinoma tissue.
IHC of GDF-9 (E322)pAb in paraffin-embedded human liver carcinoma tissue.

Western blot

Western blot of GDF-9 (E322) pAb in extracts from COLO205 cells.
Western blot of GDF-9 (E322) pAb in extracts from COLO205 cells.

Immunohistochemistry

IHC of GDF-9 (E322)pAb in paraffin-embedded human liver carcinoma tissue.
IHC of GDF-9 (E322)pAb in paraffin-embedded human liver carcinoma tissue.

Western blot

Western blot of GDF-9 (E322) pAb in extracts from COLO205 cells.
Western blot of GDF-9 (E322) pAb in extracts from COLO205 cells.

Immunohistochemistry

IHC of GDF-9 (E322)pAb in paraffin-embedded human liver carcinoma tissue.
IHC of GDF-9 (E322)pAb in paraffin-embedded human liver carcinoma tissue.

Western blot

Western blot of GDF-9 (E322) pAb in extracts from COLO205 cells.
Western blot of GDF-9 (E322) pAb in extracts from COLO205 cells.


Requested From: 
Date Requested: 6/19/2018

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