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GCLM

glutamate-cysteine ligase, modifier subunit

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.

Gene Name: glutamate-cysteine ligase, modifier subunit
Synonyms: GCLM, Gamma-ECS regulatory subunit, GLCLR, GCS light chain, GSC light chain
Target Sequences: NM_002061 NP_002052.1 P48507

☰ Filters
Antibodies (44)
ELISA Kits (13)
Proteins (7)
Over-Expression Lysate (2)
Primary (44)
Recombinant (5)
Sandwich (12)
Sandwich CLIA (1)
GCLM (64)
Human (47)
Mouse (22)
Rat (13)
Bat (3)
Bovine (4)
Chicken (1)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (5)
Pig (4)
Porcine (1)
Rabbit (4)
Zebrafish (3)
IHC (21)
IHC-P (8)
WB (39)
Flo (8)
ELISA (11)
ICC (6)
IF (12)
IP (2)
Peptide-ELISA (2)
rabbit (41)
mouse (3)
Product Group
IHCPlus (1)
IgG (30)
IgG1,k (1)
IgG2a,k (1)
monoclonal mc (2)
polyclonal pc (42)
2B8 (1)
AT2D12 (1)
96-Well Microplate (2)
96-Well Strip Plate (11)
APC (1)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (21)
aa40-251 (8)
aa246-274 (7)
aa182-231 (4)
Internal (2)
Val91 (1)
aa42-91 (1)
No (64)
Cell Lysates (1)
Plasma (7)
Serum (7)
Tissue Homogenates (5)
GST (1)
GST, N-terminus (1)
His (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
Bacteria (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
GCLM Antibody - GCLM Antibody IHC of formalin-fixed and paraffin-embedded skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.
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GCLM Rabbit anti-Human Polyclonal (aa246-274) Antibody
Mouse, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
GCLM Rabbit anti-Human Polyclonal (aa246-274) Antibody
Mouse, Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
Select
GCLM Rabbit anti-Human Polyclonal (aa246-274) (Biotin) Antibody
Mouse, Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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GCLM Rabbit anti-Human Polyclonal (aa246-274) (FITC) Antibody
Mouse, Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
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GCLM Rabbit anti-Human Polyclonal (aa246-274) (APC) Antibody
Mouse, Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
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GCLM Rabbit anti-Human Polyclonal (aa246-274) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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GCLM Rabbit anti-Human Polyclonal (aa246-274) (PE) Antibody
Mouse, Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
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GCLM Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$331
GCLM Antibody - Immunohistochemistry image of paraffin-embedded human breast cancer at a dilution of 1:100
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GCLM Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
GCLM Antibody - Anti-GCLM antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GCLM Rabbit anti-Human Polyclonal (aa182-231) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
GCLM Antibody - Anti-GCLM antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GCLM Rabbit anti-Human Polyclonal (aa182-231) (HRP) Antibody
Zebrafish, Rat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
GCLM Antibody - Anti-GCLM antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GCLM Rabbit anti-Human Polyclonal (aa182-231) (Biotin) Antibody
Zebrafish, Rat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
GCLM Antibody - Anti-GCLM antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GCLM Rabbit anti-Human Polyclonal (aa182-231) (FITC) Antibody
Zebrafish, Rat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
GCLM Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer tissue.
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GCLM Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
GCLM Antibody - Western blot of GCSm-gamma antibody
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GCLM Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GCLM Antibody - Immunofluorescence staining of GCLM in U2OS cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human GCLM polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to Cytoplasm.
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GCLM Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
50 µl/$317; 100 µl/$375; 200 µl/$473
GCLM Antibody - IHC of GCLM (V91) pAb in paraffin-embedded human prostate carcinoma tissue.
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GCLM Rabbit anti-Human Polyclonal (Val91) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
GCLM Antibody - Immunohistochemistry analysis of GCSm-γ antibody in paraffin-embedded human prostate carcinoma tissue.
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GCLM Rabbit anti-Human Polyclonal (aa42-91) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
GCLM Antibody - Immunohistochemical analysis of GCLM staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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GCLM Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
GCLM Antibody - 1:100 staining mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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GCLM Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Pig, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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GCLM Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
GCLM Antibody - Western Blot: The cell lysates of HeLa (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human GCLM antibody (1:3000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
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GCLM Mouse anti-Human Monoclonal (AT2D12) Antibody
Human
ELISA, WB
Unconjugated
50 µl/$303; 100 µl/$365
GCLM Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer using GCLM antibody at dilution of 1:100 (40x lens).
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GCLM Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
GCLM Antibody - GCLM monoclonal antibody (M01), clone 2B8 Western Blot analysis of GCLM expression in HeLa.
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GCLM Mouse anti-Human Monoclonal (2B8) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
GCLM Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
Viewing 1-25 of 64 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).