Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human GCK / Germinal Center Kinase
Western blot, ELISA
Rabbit Polyclonal to Human GCK / Germinal Center Kinase
IHC - Paraffin, Western blot
Human GCK / Germinal Center Kinase
Human, Mouse (tested or 100% immunogen sequence identity)
Ammonium sulfate precipitation
IHC - Paraffin (1:50 - 1:100)
Western blot (1:1000)
Specificity and Use
LS-E8653 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C99003. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
This Germinal Center Kinase (GCK/MAP4K2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-319 amino acids from the Central region of human Germinal Center Kinase (GCK/MAP4K2).
PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
MAP4K2 Antibody, BL44 Antibody, GC kinase Antibody, Rab8 interacting protein Antibody, RAB8IP Antibody, Rab8-interacting protein Antibody, Germinal center kinase Antibody, MEK kinase kinase 2 Antibody, MEKKK 2 Antibody
Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Acts as a MAPK kinase kinase kinase (MAP4K) and is an upstream activator of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway and to a lesser extend of the p38 MAPKs signaling pathway.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
The anti-MAP4K2 antibody is used in Western blot to detect MAP4K2 in mouse skeletal muscle tissue lysate.