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Anti-GCC2 Antibody (aa1174-1185) IHC-plus™ LS-B4938

Note: This antibody replaces LS-C87221

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular GCC2 Antibodies

Anti-GCC2 Antibody (aa1174-1185) IHC-plus™ LS-B4938
Goat Polyclonal to Human GCC2
Human
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-GCC2 Antibody (aa1581-1609, Biotin) LS-C235570
Rabbit Polyclonal (IgG) to Human GCC2
Human, Mouse
IHC, Western blot, ELISA
Biotin Conjugated
Anti-GCC2 Antibody (aa1581-1609, PE) LS-C235573
Rabbit Polyclonal (IgG) to Human GCC2
Human, Mouse
IHC, Western blot, ELISA
PE Conjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human GCC2
Human
IHC - Paraffin, ELISA
Unconjugated

Details

Human GCC2
Goat
Human (tested or 100% immunogen sequence identity)
Monkey, Rat, Bat, Hamster, Horse, Rabbit (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (3.75 µg/ml)
  • ELISA (1:16000)

Specificity and Use

GCC2 antibody was raised against synthetic peptide C-QKLTNKNNKIED from an internal region of human GCC2 (NP_055450.1; NP_852118.1). Percent identity by BLAST analysis: Human, Gibbon (100%); Gorilla, Monkey, Marmoset, Rat, Hamster, Elephant, Bat, Horse, Rabbit (92%); Mouse, Bovine, Pig (83%).
LS-E26442 - Lyophilized - 100 µg - $145.00
aa1174-1185
Human GCC2. This antibody is expected to recognise both reported isoforms (NP_055450.1and NP_852118.1).
Peptide ELISA: antibody detection limit dilution 1:16000. Western Blot: Preliminary experiments gave an approx 60kD band in Human Lymph Node and Testis lysates after 0.03 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 185kD according to NP_055450.1 and of 196kD according to NP_852118.1. The 60kD band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies / lysates? Have any further splice variants / modified forms been reported?

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About GCC2

Q8IWJ2 NM_014635 NP_055450.1

GCC2 Antibody, CLL-associated antigen KW-11 Antibody, CTCL tumor antigen se1-1 Antibody, GCC185 Antibody, GCC protein, 185-kD Antibody, Ran-binding protein 2-like 4 Antibody, RANBP2L4 Antibody, REN53 Antibody, KIAA0336 Antibody

Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi.

Immunohistochemistry

Immunohistochemistry
Anti-GCC2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4938 concentration 3.75 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-GCC2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4938 concentration 3.75 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-GCC2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4938 concentration 3.75 ug/ml.
 

Requested From: United States
Date Requested: 12/8/2016

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