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Anti-GCAP / GUCA1A Antibody (clone 2F7) LS-C197382

Ordering

Wt. Vol. Conc. Price
100 µg - - Unavailable

Most Popular GCAP / GUCA1A Antibodies

Anti-GCAP / GUCA1A Antibody (aa160-191) LS-C97757
Rabbit Polyclonal to Human GCAP / GUCA1A
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-GCAP / GUCA1A Antibody (C-Terminus, AP) LS-C244583
Rabbit Polyclonal (IgG) to Human GCAP / GUCA1A
Human
IHC, Western blot, ELISA
AP Conjugated
Anti-GCAP / GUCA1A Antibody (C-Terminus, APC) LS-C244584
Rabbit Polyclonal (IgG) to Human GCAP / GUCA1A
Human
IHC, Western blot, ELISA
APC Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 2F7] (IgG2b,k) to Human GCAP / GUCA1A
Human
Western blot, ELISA, RNA interference
Unconjugated

Details

Human GCAP / GUCA1A
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b,k Monoclonal [2F7]
Unconjugated
Protein A purified
Unmodified

Applications

  • Western blot
  • ELISA
  • RNA interference

Specificity and Use

GCAP / GUCA1A antibody was raised against gUCA1A (NP_000400, aa1-93 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Human GCAP / GUCA1A
RNAi Knockdown: Antibody validated. Western Blot: Transfected lysate, Recombinant protein.

Packaging

PBS, pH 7.2
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
For research use only.

About GCAP / GUCA1A

P43080 NM_000409 NP_000400.2

GUCA1A Antibody, C6orf131 Antibody, COD3 Antibody, CORD14 Antibody, GCAP1 Antibody, Guanylate cyclase activator 1A Antibody, GCAP Antibody, GCAP 1 Antibody, Guanylin 1, retina Antibody, Cone dystrophy 3 Antibody, DJ139D8.6 Antibody, GUCA Antibody, GUCA1 Antibody

This gene plays a role in the recovery of retinal photoreceptors from photobleaching. In the recovery phase, the phototransduction messeneger cGMP is replenished by retinal guanylyl cyclase-1 (GC1). GC1 is activated by decreasing Ca(2+) concentrations following photobleaching. The protein encoded by this gene, guanylyl cyclase activating protein 1 (GCAP1), mediates the sensitivity of GC1 to Ca(2+) concentrations.

Western blot

Western blot
Western Blot analysis of GUCA1A expression in transfected 293T cell line by GUCA1A monoclonal antibody (M04), clone 2F7.Lane 1: GUCA1A transfected lysate(22.9 KDa).Lane 2: Non-transfected lysate.

RNA interference

RNA interference
Western blot analysis of GUCA1A over-expressed 293 cell line, cotransfected with GUCA1A Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with GUCA1A monoclonal antibody (M04), clone 2F7 . GAPDH ( 36.1 kDa ) used as specificity and loading control.

Requested From: 
Date Requested: 3/29/2017

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