Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
GBP2 Antibody, GBP-2 Antibody, HuGBP-2 Antibody, Guanylate binding protein 2 Antibody, GTP-binding protein 2 Antibody
Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). GBP2 protein is a GTPase that converts GTP to GDP and GMP.
Immunohistochemical staining of paraffin-embedded Ovary tissue using anti-GBP2 mouse monoclonal antibody. (Dilution 1:50).
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-GBP2 mouse monoclonal antibody. (Dilution 1:50).
Immunohistochemical staining of paraffin-embedded endometrium tissue using anti-GBP2 mouse monoclonal antibody. (Dilution 1:50).
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-GBP2 mouse monoclonal antibody. (Dilution 1:50).
Anti-GBP2 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GBP2.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GBP2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GBP2.
HEK293T cells transfected with either pCMV6-ENTRY GBP2 (Red) or empty vector control plasmid (Blue) were immunostained with anti-GBP2 mouse monoclonal(Dilution 1:1,000), and then analyzed by flow cytometry.