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Anti-GBA / Glucosidase Beta Acid Antibody (aa352-536) LS-C185394


Wt. Vol. Conc. Price
- 100 µl 0.82 mg/ml $335

LSBio (Direct) LSBio (Direct)

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Rabbit Polyclonal (IgG) to Human GBA / Glucosidase Beta Acid
IHC - Paraffin, ICC, Western blot


Human GBA / Glucosidase Beta Acid
Human (tested or 100% immunogen sequence identity)
Rat, Bovine, Pig (at least 90% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


IHC - Paraffin (1:100 - 1:1000), ICC (1:100 - 1:1000), Western blot (1:500 - 1:3000)

Specificity and Use

GBA / Glucosidase Beta Acid antibody was raised against recombinant fragment corresponding to a region within amino acids 352 and 536 of GBA (SwissProt P04062). Percent identity by BLAST analysis: Human (100%); Pig, Bovine (92%); Rat (91%); Mouse (87%).
Human GBA
IHC-paraffin: Suggested antigen retrieval using heat mediated 10 mM Citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0).


0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
For research use only.

About GBA / Glucosidase Beta Acid

P04062 NM_000157 NP_000148.2

GBA Antibody, Acid beta-glucosidase Antibody, Alglucerase Antibody, Beta-glucocerebrosidase Antibody, GBA1 Antibody, Glucosidase, beta, acid Antibody, GLUC Antibody, GCB Antibody, Lysosomal glucocerebrosidase Antibody, Metaxin Antibody, MTXN Antibody, Glucosylceramidase Antibody, Imiglucerase Antibody

GBA / Glucosidase Beta Acid encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.


IHC of paraffin-embedded Lung CA using GBA antibody at 1:100 dilution.


Immunofluorescence of methanol-fixed HeLa using GBA antibody at 1:100 dilution.

Western blot

Western blot
Sample (30 ug of whole cell lysate). A: Hep G2. 7.5% SDS PAGE. GBA antibody diluted at 1:500

Requested From: United States
Date Requested: 11/29/2015

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