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Anti-GAPDH Antibody (clone 6C5, Biotin) LS-C188574


Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $350
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Alternate Forms of this Antibody

LS-B11003 Unconjugated
LS-C188575 DY680 Conjugated
LS-C188576 DY800 Conjugated
LS-C188577 HRP Conjugated

Most Popular GAPDH Antibodies

Anti-GAPDH Antibody (aa30-44, Magnetic beads) LS-C172169
Rabbit Polyclonal to Human GAPDH
Human, Mouse, Rat
IHC - Paraffin, IHC - Frozen, ICC, Western blot, Immunoprecipitation
Magnetic beads Conjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 6C5] (IgG1) to Rabbit GAPDH
Rabbit, Human, Monkey, Mouse, Rat, Bat, Cat, Dog, Pig, Sheep, Chicken, Xenopus, Fish, African green monkey, Green monkey, Tube-nosed bat
IHC - Paraffin, IHC - Frozen, Immunofluorescence, Western blot, Immunoprecipitation, ELISA (applications tested for the base form of this product only)
Biotin Conjugated


Rabbit GAPDH
Rabbit, Human, Monkey, Mouse, Rat, Bat, Cat, Dog, Pig, Sheep, Chicken, Xenopus, Fish, African green monkey, Green monkey, Tube-nosed bat (tested or 100% immunogen sequence identity)
Vertebrate (at least 90% immunogen sequence identity)
IgG1 Monoclonal [6C5]
Protein A purified


  • IHC - Paraffin
  • IHC - Frozen
  • Immunofluorescence
  • Western blot (1:100 - 1:1000)
  • Immunoprecipitation
  • (applications tested for the base form of this product only)

Specificity and Use

GAPDH antibody was raised against rabbit muscle GAPDH.
Recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyze the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin.
The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.


PBS, 0.09% sodium azide, 1% BSA
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.


P04406 NM_002046 NP_002037.2

GAPDH Antibody, A1 40 kd subunit Antibody, Activator 1 40 kd subunit Antibody, G3PD Antibody, GAPD Antibody, G3pdh Antibody, Rfc40 Antibody, Rf-c 40 kd subunit Antibody

Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton.


Human Kidney: Formalin Fixed, Paraffin Embedded (FFPE). This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.

Requested From: United States
Date Requested: 10/22/2016

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