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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GAP43 Antibody LS‑C42921
Antibody
GAP43 antibody LS-C42921 is an unconjugated rabbit polyclonal antibody to GAP43 from human, mouse, rat and other species. Validated for IHC, IP and WB.
Catalog
Size
Price
LS-C42921-100
100 µl
Unavailable

Popular GAP43 Products

Antibody
Species: Rat, Human, Monkey, Mouse, Bovine, Dog, Goat, Horse, Rabbit, Chicken, Zebrafish
Applications: Western blot
Anti-GAP43 antibody IHC of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B516 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human, Rat, Dog, Pig, Chicken, Primate
Applications: IHC, IHC - Paraffin
Anti-GAP43 antibody IHC of human brain, putamen, neuropil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2157 concentration 5 ug/ml.
Species: Rat, Human, Mouse, Rabbit, Chicken, Snake
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Antibody
Species: Human, Mouse, Rat
Applications: IHC
Antibody
Species: Human
Applications: ELISA

Product Description

GAP43 antibody LS-C42921 is an unconjugated rabbit polyclonal antibody to GAP43 from human, mouse, rat and other species. Validated for IHC, IP and WB.
About GAP43
This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction. P17677 NM_002045 NP_002036.1

GAP43 Antibody, Axonal membrane protein GAP-43 Antibody, B-50 Antibody, Growth associated protein 43 Antibody, Growth-associated protein 43 Antibody, Neural phosphoprotein B-50 Antibody, Neuromodulin Antibody, PP46 Antibody, GAP-43 Antibody, Protein F1 Antibody


Specifications

Target
Rat GAP43
Host
Rabbit
Reactivity
Rat, Human, Monkey, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Western blot (1:500 - 1:1000)
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GAP43 antibody was raised against purified rat GAP-43.
Specificity
Recognizes the protein designated GAP43, a neuronal protein that is expressed at elevated levels during development and also during regenerative axon growth. GAP43 (also known as neuromodulin, pp46, B-50, Protein F1 and calmodulin-binding protein P-57) is a protein of approximately 25kD that migrates on SDS-PAGE gels with an apparent size of 40-50kD. The aberrant migration is due to the unusually low abundance of hydrophobic amino acid residues. GAP43 is found tightly associated with neuronal membranes due to palmitoylation. The solubilized protein binds calmodulin, although this is reduced following protein kinase C phosphorylation of GAP43.
Presentation
Serum, 0.09% sodium azide.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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