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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GALR1 / Galanin Receptor 1 Antibody (aa60‑71) LS‑C54897
Note: This antibody replaces LS-C63475
Galanin Receptor 1 antibody LS-C54897 is an unconjugated goat polyclonal antibody to Galanin Receptor 1 (GALR1) from human, mouse, rat and other species. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C54897-100
100 µg (0.5 mg/ml)
Unavailable

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Product Description

Galanin Receptor 1 antibody LS-C54897 is an unconjugated goat polyclonal antibody to Galanin Receptor 1 (GALR1) from human, mouse, rat and other species. Validated for Peptide-ELISA and WB.
About GALR1 / Galanin Receptor 1
GalR1 is a Galanin Receptor that mediates the effects of the peptide galanin in a wide variety of tissues. Unlike GalR2, the primary signaling mechanism of GalR1 is by inhibiting adenylate cyclase through Gi. GalR1 regulates the GnRH neuroendocrine axis with its expression in POMC neurons. Pathogens like E. coli can cause diarrhea by increasing expression of Galanin Receptor 1 in the epithelial cells lining the colon, resulting in increased secretion of colonocyte chloride and fluid. P47211 NM_001480 NP_001471.2

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Specifications

Target
Human GALR1 / Galanin Receptor 1
Host
Goat
Reactivity
Human, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse (tested or 100% immunogen sequence identity)
Predicted
Monkey, Chicken, Xenopus (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.1 - 0.3 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:128000)
Failed Applications
  • IHC - Paraffin
Immunogen
Synthetic peptide C-RSKPGKPRSTTN from an internal region of human GALR1 (NP_001471.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Bovine, Dog, Bat, Horse, Opossum, Stickleback (100%); Marmoset, Turkey, Chicken, Xenopus (92%); Panda, Lizard, Pufferfish (83%).
Blocking Peptide
LS-E26232 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C54897. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa60-71
Specificity
Human GALR1.
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Antibody (0.1 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (0.1 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

Antibody (0.1 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (0.1 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

Antibody (0.1 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (0.1 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

Antibody (0.1 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (0.1 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


Requested From: 
Date Requested: 6/25/2018

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