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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GAD1 / GAD67 Antibody LS‑C149105
Antibody
GAD67 antibody LS-C149105 is an unconjugated chicken polyclonal antibody to GAD67 (GAD1) from human, mouse and rat. Validated for ICC and IHC.
Catalog
Size
Price
LS-C149105-1000
1000 µl (0.1 mg/ml)
Unavailable

Popular GAD1 / GAD67 Products

Antibody
Species: Rat, Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Anti-GAD67 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2028 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Anti-GAD67 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3027 concentration 4 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Western blot Image
Species: Mouse, Rat
Applications: IHC, Western blot

Product Description

GAD67 antibody LS-C149105 is an unconjugated chicken polyclonal antibody to GAD67 (GAD1) from human, mouse and rat. Validated for ICC and IHC.
About GAD1 / GAD67
GAD1 / GAD67 is one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Q99259 NM_000817 NP_000808.2

GAD1 Antibody, CPSQ1 Antibody, GAD-67 Antibody, Glutamate decarboxylase 1 Antibody, GAD67 Antibody, GAD Antibody, SCP Antibody


Specifications

Target
Mouse GAD1 / GAD67
Host
Chicken
Reactivity
Mouse, Human, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Ig fraction
Modifications
Unmodified
Applications
  • IHC (1:1000 - 1:2000)
  • ICC (1:1000 - 1:2000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GAD1 / GAD67 antibody was raised against synthetic peptide / keyhole limpet hemocyanin (KLH) conjugate
Specificity
This synthetic peptide corresponded to a region near the C-terminus of this gene product, and was 100% conserved between the human (Q99259, NCBI), mouse (P48318, NCBI) and rat (NP_058703, NCBI) gene products.
Usage
This GAD67 antibody recognizes only a subpopulation of GABA-ergic neurons in the cerebellar cortex, and the basis of this subpopulation is unknown. In stain cerebellar cortex, only a subpopulation of Purkinje and basket cells stain as is true for other inhibitory populations. 2% paraformaldehyde-fixed tissues recommended for immunohistochemistry and immunocytochemistry.
Presentation
Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (“PBS,” pH 7.2) with sodium azide (0.02%, w/v) added as a preservative.
Storage
May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 1 year. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/25/2018

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