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GAD1 / GAD67
glutamate decarboxylase 1 (brain, 67kDa)
GAD1 / GAD67 is one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
| Gene Name: | glutamate decarboxylase 1 (brain, 67kDa) |
| Synonyms: | GAD1, CPSQ1, GAD-67, Glutamate decarboxylase 1, GAD67, GAD, SCP |
| Target Sequences: | NM_000817 NP_000808.2 Q99259 |
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Products
Antibodies
(95)
ELISA Kits
(26)
Proteins
(11)
Type
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(1)
Custom
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Development Kit
(3)
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(2)
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(95)
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(9)
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(15)
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(1)
Target
GAD1 / GAD67
(132)
Reactivity
Human
(77)
Mouse
(61)
Rat
(49)
Bat
(4)
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(6)
Chicken
(1)
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(3)
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(7)
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(5)
Hamster
(1)
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(1)
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(7)
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(1)
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(38)
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rabbit
(67)
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(24)
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(28)
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(14)
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monoclonal mc
(24)
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(71)
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(1)
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(1)
GAD1/2391
(2)
GAD1/2563
(2)
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(2)
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(2)
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(2)
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12 x 8-Well Microstrips
(1)
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(49)
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aa1-97
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aa514-543
(7)
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(2)
440-520 aa, C-terminal
(1)
Ala492
(1)
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(1)
aa10-24
(1)
aa14-122
(1)
aa471-520
(1)
aa5-216
(1)
aa52-62
(1)
aa526-537
(1)
Publications
No
(132)
Sample Type
Adherent Cell Cultures
(1)
Cell Culture Supernatants
(2)
Cell Lysates
(5)
Plasma
(7)
Serum
(7)
Tissue Homogenates
(11)
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GST
(2)
His
(2)
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(1)
His-GST
(1)
His-S
(2)
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(3)
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(7)
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(2)
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(1)
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(1)
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(5)
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Low endotoxin level
(1)
Neuroscience
GAD1 / GAD67 Goat anti-Human Polyclonal (aa526-537) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
GAD1 / GAD67 Mouse anti-Rat Monoclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$878
GAD1 / GAD67 Mouse anti-Rat Monoclonal (APC) Antibody
Mouse, Rat, Human
IHC, WB
APC Conjugated
100 µl/$1,094
GAD1 / GAD67 Chicken anti-Human Polyclonal Antibody
Mouse, Human
ICC, IHC, WB
Unconjugated
1 ml/$1,050
GAD1 / GAD67 Chicken anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
ICC, IHC
Unconjugated
1000 µl/$666
GAD1 / GAD67 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC-P, WB
Unconjugated
100 µg/$491
GAD1 / GAD67 Mouse anti-Mouse Monoclonal (9A6) Antibody
Mouse, Rat
IHC, WB
Unconjugated
100 µg/$447
GAD1 / GAD67 Rabbit anti-Human Polyclonal (N-Terminus) (Magnetic beads) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$399
Fast Shipping
GAD1 / GAD67 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
Neuroscience
GAD1 / GAD67 Rabbit anti-Human Polyclonal (aa471-520) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
Sandwich
96-Well Strip Plate
Mouse
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$854
GAD1 / GAD67 Rabbit anti-Human Polyclonal (aa5-216) Antibody
Human
ICC, WB
Unconjugated
100 µl/$450
GAD1 / GAD67 Mouse anti-Human Monoclonal (OTI5D8) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
GAD1 / GAD67 Mouse anti-Human Monoclonal (OTI3H2) Antibody
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
GAD1 / GAD67 Mouse anti-Human Monoclonal (Carrier-free) (OTI3H2) Antibody
Dog, Human
IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
GAD1 / GAD67 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
GAD1 / GAD67 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
GAD1 / GAD67 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GAD1 / GAD67 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GAD1 / GAD67 Rabbit anti-Human Polyclonal (aa1-200) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
GAD1 / GAD67 Rabbit anti-Human Polyclonal (aa1-200) Antibody
Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
GAD1 / GAD67 Mouse anti-Human Monoclonal (OTI3G9) Antibody
IHC, IHC-P, WB
Unconjugated
100 µl/$434
GAD1 / GAD67 Mouse anti-Human Monoclonal (Carrier-free) (OTI3G9) Antibody
Human, Monkey
IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
E. coli
His-S
16.4 kDa
10 µg/$262; 50 µg/$339; 100 µg/$512; 200 µg/$642; 1 mg/$1,623; 500 µg/$1,214; 5 mg/$2,562; 2 mg/$1,796
Sandwich
96-Well Strip Plate
Human
0.39 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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product results
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